BACKGROUND Total fertilization failure (TFF) is the failure of all metaphase II oocytes to
fertilize in ART cycles. The phenomenon represents a known cause of infertility, affecting 1 …

Total fertilization failure (TFF) occurs in 1–3% of total intracytoplasmic sperm injection (ICSI)
cycles and can reoccur in subsequent cycles. Despite the high success rate with the …

BACKGROUND Oocyte activation deficiency (OAD) is attributed to the majority of cases
underlying failure of ICSI cycles, the standard treatment for male factor infertility. Oocyte …

The capacity of intracytoplasmic sperm injection (ICSI) to permit almost any type of
spermatozoa to fertilize oocytes has made it the most successful treatment for male factor …

BACKGROUND Despite the success of ICSI, total fertilization failure (TFF) still occurs in 1–
3% of all ICSI cycles. ICSI followed by assisted oocyte activation (ICSI-AOA) can restore …

Objective To investigate the extent to which assisted oocyte activation (AOA) improves
clinical outcomes in patients diagnosed with oocyte activation deficiencies (OADs). Design …

STUDY QUESTION In couples with previous fertilization failure, are reproductive outcomes
improved using ICSI followed by artificial oocyte activation (ICSI-AOA) compared with …

Research question Can oocyte-related activation deficiencies be evaluated in oocytes that
failed to fertilize after intracytoplasmic sperm injection (ICSI) combined with assisted oocyte …

STUDY QUESTION Can human oocyte calcium analysis predict fertilization success after
assisted oocyte activation (AOA) in patients experiencing fertilization failure after ICSI …

Background Artificial oocyte activation (AOA) is used to improve fertilization rate following
fertilization failure after intracytoplasmic sperm injection (ICSI). Several studies have also …