Mitogen activated protein kinases (MAPKs) are intracellular signal transduction molecules,
which connect cell‐surface receptor signals to intracellular processes. MAPKs regulate a …

Following an overview of the biochemistry of mitogen-activated protein kinase (MAPK)
pathways, the relevance of these signaling events to specific models of renal cell function …

This paper focuses on the role that mitogen‐activated protein kinases (MAPKs) play in drug‐
induced kidney injury. The MAPKs, of which there are four major classes (ERK, p38, JNK …

Mitogen-activated protein kinases (MAP kinases) are functionally connected kinases that
regulate key cellular process involved in kidney disease such as all survival, death …

Mitogen-activated protein kinases (MAPK) play a key role in the regulation of cellular
processes such as cell growth, cell differentiation, and apoptosis. However, the specific …

Tissue hypoxia/ischemia is a pathological feature of many human disorders including stroke,
myocardial infarction, hypoxic/ischemic nephropathy, as well as cancer. In the kidney, the …

Renal failure, both acute and chronic, represents an important health problem by its social,
sanitary and economic aspects. Mitogen-activated protein kinases (MAPK) are a family of …

Background. Among mitogen‐activated protein kinase (MAPK) family members, ERK
promotes proliferation or differentiation, whereas JNK and p38 are thought to inhibit cell …

Background: Chronic kidney disease (CKD) is a condition increasingly affecting millions of
individuals worldwide and is ranked as the ninth leading cause of death in the United States …

Elevated mitogen-activated protein kinase p38 (p38 MAPK) signaling has been implicated in
various experimental and human glomerulopathies, and its inhibition has proven beneficial …