Chemoresistance is a general health problem concerning infectious diseases and cancer
treatments. In this context, the worldwide dissemination of≪ pandrug≫ and≪ multidrug≫ …

Multidrug efflux mechanisms in bacteria contribute significantly to intrinsic and acquired
resistance to antimicrobial agents. Genome analysis have confirmed the broad distribution …

In this manuscript, we want to review the biochemical and genetic characteristics of the
different efflux pumps involved in both intrinsic and acquired multiresistance in non …

The process of active efflux, the last described resistance mechanism in bacteria, is one of
the important factors of acquired antibiotic resistance. Efflux systems which consist of …

Bacteria can resist to antibiotics by active exportation mediated by membrane transporters
called efflux pumps. These proteins can be specific of a class of antibiotics or responsible for …

Antibiotic resistance continues to plague antimicrobial chemotherapy of infectious disease.
And while true biocide resistance is as yet unrealized, in vitro and in vivo episodes of …

Background: Most clinical isolates that exhibit a multi-drug resistant phenotype owe that
resistance to over-expressed efflux pumps. Compounds that are efflux pump inhibitors …

Introduction The resistance-nodulation-division (RND) family is the most important group of
multidrug efflux pumps in Gram-negative bacteria. Their inhibition increases the …

Drug resistance has now become a serious concern in the domain of microbial infection.
Bacteria are becoming smarter by displaying a variety of mechanisms during drug …

Intrinsic and acquired multidrug resistance in Gram-negative bacteria owes much to the
synergy between limited outer membrane permeability and energy-dependent multidrug …