Toward a better regeneration through implant‐mediated immunomodulation: harnessing the immune responses

B Zhang, Y Su, J Zhou, Y Zheng, D Zhu - Advanced science, 2021 - Wiley Online Library
Tissue repair/regeneration, after implantation or injury, involves comprehensive
physiological processes wherein immune responses play a crucial role to enable tissue …

Immune responses to implants–a review of the implications for the design of immunomodulatory biomaterials

S Franz, S Rammelt, D Scharnweber, JC Simon - Biomaterials, 2011 - Elsevier
A key for long-term survival and function of biomaterials is that they do not elicit a detrimental
immune response. As biomaterials can have profound impacts on the host immune …

Engineering immunomodulatory biomaterials to tune the inflammatory response

A Vishwakarma, NS Bhise, MB Evangelista… - Trends in …, 2016 - cell.com
Current state-of-the-art biomedical implants and tissue engineering methods promise
technologies to improve or even restore the function of diseased organs. However, one of …

[HTML][HTML] Promoting tissue regeneration by modulating the immune system

Z Julier, AJ Park, PS Briquez, MM Martino - Acta biomaterialia, 2017 - Elsevier
The immune system plays a central role in tissue repair and regeneration. Indeed, the
immune response to tissue injury is crucial in determining the speed and the outcome of the …

[图书][B] The immune response to implanted materials and devices

B Corradetti, ME Scarritt, R Londono, SF Badylak… - 2017 - Springer
This textbook is intended to be a resource for biomaterial scientists and biomedical
engineers, in both industry and academia, interested in the development of smart strategies …

Harnessing the innate and adaptive immune system for tissue repair and regeneration: Considering more than macrophages

LC Shanley, OR Mahon, DJ Kelly, A Dunne - Acta Biomaterialia, 2021 - Elsevier
Tissue healing and regeneration is a complex, choreographed, spatiotemporal process
involving a plethora of cell types, the activity of which is stringently regulated in order for …

Immunomodulatory strategies for bone regeneration: a review from the perspective of disease types

N Su, C Villicana, F Yang - Biomaterials, 2022 - Elsevier
Tissue engineering strategies for treating bone loss to date have largely focused on
targeting stem cells or vascularization. Immune cells, including macrophages and T cells …

Immunomodulatory biomaterials for tissue repair

R Whitaker, B Hernaez-Estrada… - Chemical …, 2021 - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Innate immunity and biomaterials at the nexus: friends or foes

SN Christo, KR Diener, A Bachhuka… - BioMed research …, 2015 - Wiley Online Library
Biomaterial implants are an established part of medical practice, encompassing a broad
range of devices that widely differ in function and structural composition. However, one …

[HTML][HTML] Biomaterials: foreign bodies or tuners for the immune response?

E Mariani, G Lisignoli, RM Borzì… - International journal of …, 2019 - mdpi.com
The perspectives of regenerative medicine are still severely hampered by the host response
to biomaterial implantation, despite the robustness of technologies that hold the promise to …