Biomaterials play a core role in cartilage repair and regeneration. The success or failure of
an implanted biomaterial is largely dependent on host response following implantation. Host …

With an increasingly aging society, bone defects and fractures have become significant
threats to human health and quality of life. Currently, autologous and allogeneic bone grafts …

An immune response involves the action of all types of macrophages, classically activated
subtype (M1) in the early inflammatory phase and regulatory and wound-healing subtypes …

Proinflammatory cytokines are infamous for their catabolic effects on tissues and joints in
both inflammatory diseases and following the implantation of biomedical devices. However …

Neutrophils, the first immune cells infiltrating an implantation site, play a central role in the
immune response to biomaterial-based implants. They initiate inflammation by secreting pro …

Novel transplantation techniques are currently under development to preserve the function
of impaired tissues or organs. While current technologies can enhance the survival of …

Control of inflammation is indispensable for optimal oral wound healing and tissue
regeneration. Several biomaterials have been used to enhance the regenerative outcomes; …

The immune system, best known as the first line of defense against invading pathogens, is
integral to tissue development, homeostasis, and wound repair. In recent years, there has …

Technologies that induce antigen-specific immune tolerance by mimicking naturally
occurring mechanisms have the potential to revolutionize the treatment of many immune …

Immunotherapy is used to regulate systemic hyperactivation or hypoactivation to treat
various diseases. Biomaterial‐based immunotherapy systems can improve therapeutic …