Immunomodulatory functions of mesenchymal stem cells in tissue engineering

H Li, S Shen, H Fu, Z Wang, X Li, X Sui… - Stem cells …, 2019 - Wiley Online Library
The inflammatory response to chronic injury affects tissue regeneration and has become an
important factor influencing the prognosis of patients. In previous stem cell treatments, it was …

Macroscale biomaterials strategies for local immunomodulation

MO Dellacherie, BR Seo, DJ Mooney - Nature Reviews Materials, 2019 - nature.com
The immune system plays key roles in tissue homeostatic and disease processes, and
manipulation of innate and adaptive immune responses is of great promise for a wide array …

Biomaterials‐based modulation of the immune system

AB Gardner, SKC Lee, EC Woods… - BioMed research …, 2013 - Wiley Online Library
The immune system is traditionally considered from the perspective of defending against
bacterial or viral infections. However, foreign materials like implants can also illicit immune …

Bioactive materials: a comprehensive review on interactions with biological microenvironment based on the immune response

S Nour, N Baheiraei, R Imani, N Rabiee… - Journal of Bionic …, 2019 - Springer
Application of “bioactive materials”, as a modified version of biomaterials, can optimize the
response of the biological system due to their surface reactivity and formation of strong …

Extracellular matrix bioscaffolds as immunomodulatory biomaterials

JL Dziki, L Huleihel, ME Scarritt… - Tissue Engineering Part …, 2017 - liebertpub.com
Suppression of the recipient immune response is a common component of tissue and organ
transplantation strategies and has also been used as a method of mitigating the …

The host immune response to tissue-engineered organs: current problems and future directions

K Wiles, JM Fishman, P De Coppi… - Tissue Engineering Part …, 2016 - liebertpub.com
As the global health burden of chronic disease increases, end-stage organ failure has
become a costly and intractable problem. De novo organ creation is one of the long-term …

Advanced strategies for modulation of the material–macrophage interface

L Davenport Huyer, S Pascual‐Gil… - Advanced Functional …, 2020 - Wiley Online Library
Biomaterials are becoming increasingly crucial for healthcare solutions, with extensive use
in the field of tissue engineering and drug delivery. After implantation, biomaterials trigger an …

Biomaterials for enhancing anti-cancer immunity

ST Koshy, DJ Mooney - Current opinion in biotechnology, 2016 - Elsevier
Highlights•Biomaterials can potentially improve the safety and efficacy of cancer
immunotherapy.•Biomaterials scaffolds can program immune cell function in peripheral …

Targeted modulation of immune cells and tissues using engineered biomaterials

P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

Biomaterials as local niches for immunomodulation

K Adu-Berchie, DJ Mooney - Accounts of chemical research, 2020 - ACS Publications
Conspectus A major function of the immune system is to detect threat from foreign invaders,
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …