The two main components of a tissue engineered device are the transplanted cells and the
biomaterial, creating a device for the restoration or modification of tissue or organ function …

The degree of tissue injuries such as the level of scarring or organ dysfunction, and the
immune response against them primarily determine the outcome and speed of healing …

The immune system plays a critical role in wound healing and the response to biomaterials.
Biomaterials-directed regenerative immunology is an immunoengineering strategy that …

Macrophages have long been known for their phagocytic capabilities and immune defence;
however, their role in healing is being increasingly recognized in recent years due to their …

Limited motor activity due to the loss of natural structure impedes recovery in patients
suffering from tendon-to-bone injury. Conventional biomaterials focus on strengthening the …

It is widely known that bone has intrinsic capacity to self-regenerate after injury. However,
the physiological regeneration process can be impaired when there is an extensive …

Adoptive immunotherapies based on the transfer of functional immune cells hold great
promise in treating a wide range of malignant diseases, especially cancers, autoimmune …

Vaccines and immunotherapies have provided enormous improvements for public health,
but there are fundamental disconnects between where most studies are performed—in cell …

Implants, transplants, and implantable biomedical devices are mainstream solutions for a
wide variety of human pathologies. One of the persistent problems around nondegradable …

Despite the rapid development of therapeutic approaches for skin repair, chronic wounds
such as diabetic foot ulcers remain an unaddressed problem that affects millions of people …