Transplantable Tissue—Immune and Genome Engineering Dramatic advancements in the
use of synthetic and mechanical devices to replace tissues have been made, but restoring …

A coordinated interaction between osteogenesis and osteoimmune microenvironment is
essential for successful bone healing. In particular, macrophages play a central regulatory …

Biomaterials as bone substitutes are always considered as foreign bodies that can trigger
host immune responses. Traditional designing principles have been always aimed at …

The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

The extracellular matrix (ECM) is a complex and dynamic structural scaffold for cells within
tissues and plays an important role in regulating cell function. Recently it has become …

The inflammatory response following implantation of a biomaterial is one of the major
regulatory aspects of the overall regenerative process. The progress of inflammation …

The demand for biomaterials that promote the repair, replacement, or restoration of hard and
soft tissues continues to grow as the population ages. Traditionally, smart biomaterials have …

The past decade has witnessed the explosive development of cancer immunotherapies.
Nevertheless, low immunogenicity, limited specificity, poor delivery efficiency, and off‐target …

Macrophage immunotherapy is an emerging treatment strategy that modulates the immune
system to promote wound healing. The functionality and regeneration of tissue depend on …

Despite various studies to minimize host reaction following a biomaterial implantation, an
appealing strategy in regenerative medicine is to actively use such an immune response to …