Critical bone defects and related delayed union and nonunion are still worldwide problems
to be solved. Bone tissue engineering is mainly aimed at achieving satisfactory bone …

The immune response of the host towards a decellularized scaffold is complex. Not only can
a number of immune cells influence this process, but also the characteristics, preparation …

We summarize research approaches and findings on bone healing and regeneration that
were presented at a workshop at the 60th annual meeting of the Orthopedic Research …

Delayed healing or nonhealing of bone is an important clinical concern. Although bone, one
of the two tissues with scar-free healing capacity, heals in most cases, healing is delayed in …

Tissue engineering with scaffolds provides novel prospects for bone/cartilage damage
healing. Previous studies mainly focus on the development of physical/chemical property of …

The present study tests the hypothesis that transient, early-stage shifts in macrophage
polarization at the tissue-implant interface from a pro-inflammatory (M1) to an anti …

In situ tissue engineering using bioresorbable material implants-or scaffolds-that harness
the patient's immune response while guiding neotissue formation at the site of implantation …

The immune responses are involved in every stage after implantation but the reported
immune-regulated materials only work at the beginning without fully considering the different …

The substantially growing gap between suitable donors and patients waiting for new organ
transplantation has compelled tissue engineers to look for suitable patient-specific …

One goal of tissue engineering is to replace lost or compromised tissue function, and an
approach to this is to control the interplay between materials (scaffolds), cells and growth …