Clinical position of lacidipine, a new dihydropyridine calcium antagonist, in the treatment of hypertension

G Leonetti - Journal of cardiovascular pharmacology, 1991 - journals.lww.com
Lacidipine is a calcium antagonist of the dihydropyridine group that is highly selective for
vascular tissues. It has been tested during the last few years for the treatment of arterial …

Long-term antihypertensive treatment with lacidipine, a new long-acting calcium antagonist

R Nami, P Rizzini, P Buracchi, G Pavese… - Journal of …, 1991 - journals.lww.com
Eleven centers in Tuscany, Italy, recruited 96 patients (aged 21-75 years) with mild-to-
moderate essential hypertension [diastolic blood pressure (DBP) 95-115 mm Hg; systolic …

Lacidipine: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of hypertension

C Rhoda Lee, HM Bryson - Drugs, 1994 - Springer
Synopsis Lacidipine is an orally administered calcium channel blocker of the
dihydropyridine class, which shows selectivity for vascular smooth muscle over cardiac …

The impact of lacidipine, a novel dihydropyridine calcium antagonist, on carbohydrate and lipid metabolism

C Spieker, W Zidek - Journal of Cardiovascular Pharmacology, 1995 - journals.lww.com
In an open, multicenter study, the calcium antagonist lacidipine was tested for efficacy and
safety, particularly with respect to any influence on lipid and carbohydrate metabolism. The …

Safety profile of lacidipine: a review of clinical data

CA Endersby, EG Brown… - Journal of cardiovascular …, 1991 - journals.lww.com
The clinical safety of the new dihydropyridine calcium antagonist lacidipine was assessed in
14 clinical trials, including 1,372 patients treated with lacidipine and 687 treated with an …

Relative efficacy and tolerability of lacidipine and amlodipine in patients with mild-to-moderate hypertension: a randomized double-blind study

CP Lau, BMY Cheung - Journal of cardiovascular pharmacology, 1996 - journals.lww.com
Calcium channel blockers are increasingly used in the treatment of hypertension. Newer
calcium channel blockers of the dihydropyridine group have longer elimination half-lives …

Calcium Antagonist Antihypertensive Treatment of Non-Insulin-Dependent Diabetics: Efficacy and Safety of Lacidipine Versus Nifedipine SR

M Gulizia, R Valenti, F Platania… - Journal of …, 1994 - journals.lww.com
Arterial hypertension is a chronic condition regarded as one of the main risk factors for
development of coronary atherosclerosis. As dyslipidemia and reduced glucose tolerance …

Effect of lacidipine, a long-acting calcium antagonist, on hypertension and lipids: a 1 year follow-up

S Soro, LA Ferrara - European journal of clinical pharmacology, 1991 - Springer
The effect of lacidipine, a dihydropyridine calcium antagonist on lipid metabolism, has been
followed in 8 patients with uncomplicated mild to moderate essential hypertension treated …

A long-term study comparing lacidipine and nifedipine SR in hypertensive patients: safety data

G Leonetti, S Salvi - Journal of Cardiovascular Pharmacology, 1994 - journals.lww.com
The clinical safety of lacidipine, a new dihydropyridine calcium antagonist, has been
assessed in a longterm, comparative study in hypertensive patients. Slowrelease (SR) …

Comparative study of lacidipine and nicidipine SR in the treatment of hypertension: an Italian multicenter study

G Leonetti - Journal of cardiovascular pharmacology, 1991 - journals.lww.com
The aim of this study was to compare the antihypertensive efficacy and tolerability of
lacidipine, a new dihydropyridine calcium antagonist, and slow-release nifedipine (SR) in …