Safety aspects of treatment with lacidipine—a slow-onset, long-acting calcium antagonist

LH Lindholm, P Tcherdakoff, A Zanchetti - Blood pressure, 1996 - Taylor & Francis
Objective: The aim was to review the clinical safety profile of lacidipine with the help of the
rather comprehensive datafile of the manufacturer-a novel approach which may be of some …

Safety of the calcium antagonist lacidipine evaluated from a phase III–IV trial database

LH Lindholm, P Tcherdakoff… - Journal of Hypertension, 1996 - journals.lww.com
Objective We reviewed the clinical safety profile of lacidipine with the help of the rather
comprehensive data file of the manufacturer. Although a number of prospective, randomly …

Efficacy and safety of lacidipine, a new long-lasting calcium antagonist, in elderly hypertensive patients

P Rizzini, C Castello, S Salvi… - Journal of cardiovascular …, 1991 - journals.lww.com
Elderly patients are becoming a greater proportion of the hypertensive population. In
addition, they may respond differently to drugs, both pharmacodynam-ically and …

Lacidipine: a review of its use in the management of hypertension

PL McCormack, AJ Wagstaff - Drugs, 2003 - Springer
Summary Abstract Lacidipine (Caldine®, Lacimen®, Lacipil®, Midotens®, Motens®) is a
once-daily, orally-administered, lipophilic dihydropyridine calcium antagonist with an …

Selection of initial and maintenance dosages for lacidipine, a new once-daily calcium antagonist for the treatment of hypertension

M Perelman - Journal of cardiovascular pharmacology, 1991 - journals.lww.com
Selection of the appropriate dose of a new drug for initiation of treatment and then for
maintenance is a complicated task. It requires the careful assessment and weighing of …

A double-blind comparison of the efficacy and safety of lacidipine and hydrochlorothiazide in essential hypertension

M Chiariello… - Journal of …, 1991 - journals.lww.com
This multicenter study was designed to assess the clinical efficacy and safety of the new
once-daily calcium antagonist lacidipine in the treatment of mild-to-moderate essential …

Vascular effects of lacidipine: a review of animal and human data

G Mancia, AU Ferrarit, C Giannattasio… - Journal of …, 1993 - journals.lww.com
Aim: To compare the vascular effects of lacidipine with those of other calcium antagonists.
Methods: A review of published studies. Results: Experimental studies have shown that for a …

Efficacy and safety evaluation of lacidipine compared with amlodipine in mild-to-moderate hypertensive patients

D Lombardo, F Raimondi - Journal of Cardiovascular …, 1994 - journals.lww.com
Hypertension is well recognized to be an important cardiovascular risk factor and
antihypertensive therapy has been shown to decrease cardiovascular mortality and …

An assessment of lacidipine and atenolol in mild to moderate hypertension.

D Lyons, G Fowler, J Webster, ST Hall… - British journal of …, 1994 - Wiley Online Library
1. The aim of this randomised, double‐blind four way crossover study was to assess the
interaction between the new calcium antagonist, lacidipine and atenolol, in patients with …

Impact of calcium antagonists on the cardiovascular system: experience with lacidipine

E Kuschnir - Drugs, 1999 - Springer
The evaluation of haemodynamic patterns in hypertensive patients by radionuclide
techniques and a tomographic gamma camera has revealed differences between older and …