Sarcopenia and Cognitive decline in older adults: targeting the muscle–brain Axis
Declines in physical performance and cognition are commonly observed in older adults. The
geroscience paradigm posits that a set of processes and pathways shared among age …
geroscience paradigm posits that a set of processes and pathways shared among age …
Muscle–Brain crosstalk in cognitive impairment
Sarcopenia is an age-related, involuntary loss of skeletal muscle mass and strength.
Alzheimer's disease (AD) is the most common cause of dementia in elderly adults. To date …
Alzheimer's disease (AD) is the most common cause of dementia in elderly adults. To date …
Sarcopenia and cognitive function: role of myokines in muscle brain cross-talk
L Scisciola, RA Fontanella, Surina, V Cataldo… - Life, 2021 - mdpi.com
Sarcopenia is a geriatric syndrome characterized by the progressive degeneration of muscle
mass and function, and it is associated with severe complications, which are falls, functional …
mass and function, and it is associated with severe complications, which are falls, functional …
Pathophysiological mechanisms explaining the association between low skeletal muscle mass and cognitive function
SJ Oudbier, J Goh, SMLM Looijaard… - The Journals of …, 2022 - academic.oup.com
Low skeletal muscle mass is associated with cognitive impairment and dementia in older
adults. This review describes the possible underlying pathophysiological mechanisms …
adults. This review describes the possible underlying pathophysiological mechanisms …
Sarcopenia and neuroscience: learning to communicate
In the 1990s and early 2000s, the common definition for sarcopenia was age-related loss of
skeletal muscle, and low levels of muscle mass were central to sarcopenia diagnosis. In …
skeletal muscle, and low levels of muscle mass were central to sarcopenia diagnosis. In …
Sarcopenia and the common mental disorders: a potential regulatory role of skeletal muscle on brain function?
While it is understood that body composition impacts on physical conditions, such as
diabetes and cardiovascular disease, it is only now apparent that body composition might …
diabetes and cardiovascular disease, it is only now apparent that body composition might …
Sarcopenia: aging-related loss of muscle mass and function
Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …
diminishes quality of life, and can lead to fall-related injuries, which require costly …
Searching for a mitochondrial root to the decline in muscle function with ageing
M Gonzalez‐Freire, F Adelnia… - Journal of cachexia …, 2018 - Wiley Online Library
Sarcopenia, the age‐related loss of muscle mass and strength, is linked to a range of
adverse outcomes, such as impaired physical performance, cognitive function, and mortality …
adverse outcomes, such as impaired physical performance, cognitive function, and mortality …
Skeletal muscle health and cognitive function: a narrative review
Sarcopenia is the loss of skeletal muscle mass and function with advancing age. It involves
both complex genetic and modifiable risk factors, such as lack of exercise, malnutrition and …
both complex genetic and modifiable risk factors, such as lack of exercise, malnutrition and …
Neural mechanisms of age-related loss of muscle performance and physical function
BC Clark - The Journals of Gerontology: Series A, 2023 - academic.oup.com
Background: This article discusses the putative neural mechanisms of age-related muscle
weakness within the broader context of the development of function-promoting therapies for …
weakness within the broader context of the development of function-promoting therapies for …