Reactivity of 5-HT1A receptor in adult rats after neonatal noradrenergic neurons' lesion—Implications for antidepressant-like action

J Dabrowska, P Nowak, R Brus - Brain research, 2008 - Elsevier
The aim of this study was to assess the 5-HT1A receptor reactivity after neonatal
noradrenergic neurons' lesion. DSP-4 (N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine), 50 …

Desensitization of 5-HT1A autoreceptors induced by neonatal DSP-4 treatment

J Dąbrowska, P Nowak, R Brus - European neuropsychopharmacology, 2007 - Elsevier
To examine the effect of noradrenergic lesion on the reactivity of central 5-HT1A receptors,
DSP-4 (50 mg/kg) was administered neonatally 30min after zimelidine (10 mg/kg) …

Neonatal DSP-4 treatment impairs 5-HT1B receptor reactivity in adult rats. Behavioral and biochemical studies

M Ferdyn-Drosik, P Nowak, K Bojanek, M Bałasz… - Pharmacological …, 2010 - Springer
To examine the effect of a central noradrenergic lesion on the reactivity of the 5-HT 1B
receptor we compared intact male rats with rats in which noradrenergic nerve terminals were …

The effect of central noradrenergic system lesion on dopamine (DA) and serotonin (5-HT) synthesis rate following administration of 5-HT3 receptor ligands in chosen …

W Roczniak, M Babuśka-Roczniak, J Kwapuliński… - Pharmacological …, 2015 - Elsevier
Introduction Since little has been known about the effect of the central noradrenergic system
on the reactivity of serotonin 5-HT 3 receptors, the aim of the current study was to find out …

Altered expression of 5-HT1A receptors in adult rats induced by neonatal treatment with clomipramine

O Limón-Morales, C Soria-Fregozo… - Physiology & …, 2014 - Elsevier
Chronic administration of clomipramine (CMI) to neonatal rats produces behaviors that
resemble a depressive state in adulthood. Dysfunctions in the activity of the central nervous …

Prenatal exposure of rats to antidepressant drugs down-regulates beta-adrenoceptors and 5-HT2 receptors in cerebral cortex: lack of correlation between 5-HT2 …

ML De Ceballos, A Benedi, C Urdin, J Del Rio - Neuropharmacology, 1985 - Elsevier
Abstract Changes in the binding of β-adrenoceptors and 5-HT 2 receptors and in behaviour
mediated by serotonin were studied after either acute treatment or prenatal exposure of rats …

Effect of chronic administration of antidepressant drugs on 5-HT2-mediated behavior in the rat following noradrenergic or serotonergic denervation

AS Eison, FD Yocca, G Gianutsos - Journal of Neural Transmission …, 1991 - Springer
Chronic (14 day) administration of several pharmacologically-distinct antidepressant drugs
resulted in marked reductions in the serotonin 2 (5-HT 2)-mediated quipazine-induced head …

Hypersensitivity to serotonin and its agonists in serotonin-hyperinnervated neostriatum after neonatal dopamine denervation

M El Mansari, F Radja, A Ferron, TA Reader… - European journal of …, 1994 - Elsevier
Neonatal destruction of the nigrostriatal dopamine projection by intraventricular 6-
hydroxydopamine leads to a serotonin (5-hydroxytryptamine, 5-HT) hyperinnervation of the …

Modification of serotonin neuron properties in mice lacking 5-HT1A receptors

M Richer, R Hen, P Blier - European journal of pharmacology, 2002 - Elsevier
Using null mutant mice for the 5-HT1A receptor (5-HT1A−/−), extracellular
electrophysiological recordings were first conducted to evaluate the impact of its genetic …

Functional correlates for 5-HT1A receptors in maternally deprived rats displaying anxiety and depression-like behaviors

L Lambás-Señas, O Mnie-Filali, V Certin… - Progress in Neuro …, 2009 - Elsevier
Maternal separation is known to induce long-term changes in neuroendocrine and
emotional responsiveness to stress in a large variety of models. We examined an animal …