Pseudomonas aeruginosa is a widespread environmental bacterium and an opportunistic
pathogen that represents a health hazard due to its production of virulence factors and its …

Extensive use of next-generation sequencing (NGS) for pathogen profiling has the potential
to transform our understanding of how genomic plasticity contributes to phenotypic …

Pseudomonas aeruginosa is an opportunistic pathogen that causes a wide range of acute
and chronic infections. An increasing number of isolates have mutations that make them …

Extensive use of next-generation sequencing has the potential to transform our knowledge
on how genomic variation within bacterial species impacts phenotypic versatility. Because …

Antibiotic resistance has become a serious threat to human health (WHO Antibacterial
Agents in Clinical Development: an Analysis of the Antibacterial Clinical Development …

Phenotypic variability among bacteria depends on gene expression in response to different
environments, and it also reflects differences in genomic structure. In this study, we analyzed …

The advent of next-generation sequencing technology has revolutionized the field of
prokaryotic genetics and genomics by allowing interrogation of entire genomes …

Whole-genome shotgun sequencing was used to study the sequence variation of three
Pseudomonas aeruginosa isolates, two from clonal infections of cystic fibrosis patients and …

Pseudomonas aeruginosa is the leading cause of nosocomial infections, particularly in
immunocompromised, cancer, burn and cystic fibrosis patients. Development of novel …

Pseudomonas aeruginosa strains exhibit significant variability in pathogenicity and
ecological flexibility. Such interstrain differences reflect the dynamic nature of the P …