Phylogenomic and comparative genomic studies robustly demarcate two distinct clades of Pseudomonas aeruginosa strains: proposal to transfer the strains from an outlier clade …

B Rudra, L Duncan, AJ Shah… - … of Systematic and …, 2022 - microbiologyresearch.org
The strains of Pseudomonas aeruginosa exhibit considerable differences in their genotypic
and pathogenic properties. To clarify their evolutionary/taxonomic relationships …

[HTML][HTML] Comparative transcriptome analyses of Pseudomonas aeruginosa

D Balasubramanian, K Mathee - Human genomics, 2009 - Springer
One of the hallmarks of bacterial survival is their ability to adapt rapidly to changing
environmental conditions. Niche adaptation is a response to the signals received that are …

[PDF][PDF] Genome diversity of Pseudomonas aeruginosa

J Klockgether, D Würdemann… - Pseudomonas …, 2008 - researchgate.net
Abstract The G+ C rich Pseudomonas aeruginosa chromosome consists of a conserved core
and a variable accessory part. The core genomes of P. aeruginosa strains are largely …

[HTML][HTML] Advances in understanding Pseudomonas

B Tümmler, L Wiehlmann, J Klockgether… - F1000prime …, 2014 - ncbi.nlm.nih.gov
Pseudomonas aeruginosa, the type species of pseudomonads, is an opportunistic pathogen
that colonizes a wide range of niches. Current genome sequencing projects are producing …

Integrated whole‐genome screening for Pseudomonas aeruginosa virulence genes using multiple disease models reveals that pathogenicity is host specific

JF Dubern, C Cigana, M De Simone… - Environmental …, 2015 - Wiley Online Library
P seudomonas aeruginosa is a multi‐host opportunistic pathogen causing a wide range of
diseases because of the armoury of virulence factors it produces, and it is difficult to …

[HTML][HTML] A Comprehensive Analysis of In Vitro and In Vivo Genetic Fitness of Pseudomonas aeruginosa Using High-Throughput Sequencing of Transposon …

D Skurnik, D Roux, H Aschard, V Cattoir… - PLoS …, 2013 - journals.plos.org
High-throughput sequencing of transposon (Tn) libraries created within entire genomes
identifies and quantifies the contribution of individual genes and operons to the fitness of …

[HTML][HTML] Genome Analysis of Pseudomonas aeruginosa Strains from Chronically Infected Patients with High Levels of Persister Formation

AA Baiomy, FE Serry, AA Kadry, G Yahya, S Doijad… - Pathogens, 2023 - mdpi.com
The appearance of persister cells with low metabolic rates are key factors leading to
antibiotic treatment failure. Such persisters are multidrug tolerant and play a key role in the …

Genome-Wide Patterns of Recombination in the Opportunistic Human Pathogen Pseudomonas aeruginosa

JR Dettman, N Rodrigue… - Genome biology and …, 2015 - academic.oup.com
The bacterium Pseudomonas aeruginosa is a significant cause of acute nosocomial
infections as well as chronic respiratory infections in patients with cystic fibrosis (CF). Recent …

The Pseudomonas aeruginosa genome How do we use it to develop strategies for the treatment of patients with cystic fibrosis and Pseudomonas infections?

AL Erwin, DR VanDevanter - Current Opinion in Pulmonary …, 2002 - journals.lww.com
In the 2 years since the complete sequence of Pseudomonas aeruginosa strain PAO1 was
published, at least 200 papers have been published describing research that made use of …

[HTML][HTML] An integrated genomic regulatory network of virulence-related transcriptional factors in Pseudomonas aeruginosa

H Huang, X Shao, Y Xie, T Wang, Y Zhang… - Nature …, 2019 - nature.com
The virulence of Pseudomonas aeruginosa, a Gram-negative opportunistic pathogen, is
regulated by many transcriptional factors (TFs) that control the expression of quorum …