Small-cell lung cancer
CM Rudin, E Brambilla, C Faivre-Finn… - Nature Reviews Disease …, 2021 - nature.com
Small-cell lung cancer (SCLC) represents about 15% of all lung cancers and is marked by
an exceptionally high proliferative rate, strong predilection for early metastasis and poor …
an exceptionally high proliferative rate, strong predilection for early metastasis and poor …
[HTML][HTML] Small cell lung cancer: can recent advances in biology and molecular biology be translated into improved outcomes?
Small cell lung cancer (SCLC) is one of the four major histological types of lung cancer. The
incidence of SCLC in developed countries has declined in recent years, presumably …
incidence of SCLC in developed countries has declined in recent years, presumably …
Clinical insights into small cell lung cancer: Tumor heterogeneity, diagnosis, therapy, and future directions
Z Megyesfalvi, CM Gay, H Popper… - CA: a cancer journal …, 2023 - Wiley Online Library
Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity.
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …
It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority …
[HTML][HTML] Small cell lung cancer (SCLC): no treatment advances in recent years
F Koinis, A Kotsakis, V Georgoulias - Translational lung cancer …, 2016 - ncbi.nlm.nih.gov
Small cell lung cancer (SCLC) is an aggressive malignancy with a distinct natural history
and dismal prognosis. Given its predisposition for early dissemination, patients are …
and dismal prognosis. Given its predisposition for early dissemination, patients are …
Small-cell lung cancer: what we know, what we need to know and the path forward
Small-cell lung cancer (SCLC) is a deadly tumour accounting for approximately 15% of lung
cancers and is pathologically, molecularly, biologically and clinically very different from other …
cancers and is pathologically, molecularly, biologically and clinically very different from other …
[HTML][HTML] Small cell lung cancer: a slightly less orphan disease after immunotherapy
Highlights•ICIs have shifted the treatment paradigm to improve overall survival in advanced
SCLC.•The magnitude of immune-chemotherapy strategy is still modest. The …
SCLC.•The magnitude of immune-chemotherapy strategy is still modest. The …
Small cell lung cancer: where do we go from here?
Small cell lung cancer (SCLC) is an aggressive disease that accounts for approximately
14% of all lung cancers. In the United States, approximately 31,000 patients are diagnosed …
14% of all lung cancers. In the United States, approximately 31,000 patients are diagnosed …
[HTML][HTML] Update on the biology, management, and treatment of small cell lung cancer (SCLC)
A Saltos, M Shafique, A Chiappori - Frontiers in oncology, 2020 - frontiersin.org
Small-cell lung cancer (SCLC) accounts for 13–15% of all new lung cancer cases in the US.
The tumor has a tendency to disseminate early resulting in 80–85% of patients being …
The tumor has a tendency to disseminate early resulting in 80–85% of patients being …
[HTML][HTML] Cellular and molecular biology of small cell lung cancer: an overview
Although the incidence of small cell lung cancer (SCLC) has declined during the past 30
years, it remains a frustrating disease to research and treat. Numerous attempts to enhance …
years, it remains a frustrating disease to research and treat. Numerous attempts to enhance …
[HTML][HTML] Signal pathways and precision therapy of small-cell lung cancer
M Yuan, Y Zhao, HT Arkenau, T Lao, L Chu… - Signal transduction and …, 2022 - nature.com
Small-cell lung cancer (SCLC) encounters up 15% of all lung cancers, and is characterized
by a high rate of proliferation, a tendency for early metastasis and generally poor prognosis …
by a high rate of proliferation, a tendency for early metastasis and generally poor prognosis …