[PDF][PDF] Characterization and proteome of circulating extracellular vesicles as potential biomarkers for NASH

D Povero, H Yamashita, W Ren… - Hepatology …, 2020 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is currently one of most common forms of chronic
liver disease globally. NAFLD represents a wide spectrum of liver involvement from …

[HTML][HTML] Extracellular vesicles: from biomarkers to therapeutic tools

S Bernardi, C Balbi - Biology, 2020 - mdpi.com
Intercellular communication is an essential hallmark of multicellular organisms and can be
mediated through direct cell–cell contact or transfer of secreted molecules. In the last two …

[HTML][HTML] Extracellular vesicles in NAFLD/ALD: from pathobiology to therapy

A Hernández, JP Arab, D Reyes, A Lapitz, H Moshage… - Cells, 2020 - mdpi.com
In recent years, knowledge on the biology and pathobiology of extracellular vesicles (EVs)
has exploded. EVs are submicron membrane-bound structures secreted from different cell …

Extracellular vesicles: translational challenges and opportunities

H Clemmens, DW Lambert - Biochemical Society Transactions, 2018 - portlandpress.com
Extracellular vesicles (EVs) are a heterogeneous group of small lipid-enclosed structures
with myriad roles in physiology and disease. The recent surge of interest in EVs has led to …

Microvesicles and exosomes in metabolic diseases and inflammation

L Dini, S Tacconi, E Carata, AM Tata, C Vergallo… - Cytokine & Growth …, 2020 - Elsevier
Metabolic diseases are based on a dysregulated crosstalk between various cells such as
adipocytes, hepatocytes and immune cells. Generally, hormones and metabolites mediate …

Advances on liver cell‐derived exosomes in liver diseases

Y Jiao, P Xu, H Shi, D Chen… - Journal of cellular and …, 2021 - Wiley Online Library
Exosomes are extracellular vesicles with diameters ranging from 30 to 150 nm, which
contain several donor cell‐associated proteins as well as mRNA, miRNA, and lipids and …

Extracellular vesicles: mechanisms in human health and disease

M Malloci, L Perdomo, M Veerasamy… - Antioxidants & redox …, 2019 - liebertpub.com
Abstract Significance: Secreted extracellular vesicles (EVs) are now considered veritable
entities for diagnosis, prognosis, and therapeutics. These structures are able to interact with …

The emerging roles of microvesicles in liver diseases

S Lemoinne, D Thabut, C Housset, R Moreau… - Nature reviews …, 2014 - nature.com
Microvesicles (MVs) are extracellular vesicles released by virtually all cells, under both
physiological and pathological conditions. They contain lipids, proteins, RNAs and …

[HTML][HTML] Liver-derived exosomes and their implications in liver pathobiology

S Sung, J Kim, Y Jung - International journal of molecular sciences, 2018 - mdpi.com
The liver has a wide range of physiological functions in the body, and its health is
maintained by complex cross-talk among hepatic cells, including parenchymal hepatocytes …

[HTML][HTML] Roles of macrophages and exosomes in liver diseases

M Shen, Y Shen, X Fan, R Men, T Ye, L Yang - Frontiers in medicine, 2020 - frontiersin.org
Exosomes are small discoid extracellular vesicles (EVs) originating from endosomes that
are 30–150 nm in diameter and have a double lipid layer. They participate in the immune …