Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles

SM Davidson, CM Boulanger, E Aikawa… - Cardiovascular …, 2023 - academic.oup.com
Extracellular vesicles (EVs) are nanosized vesicles with a lipid bilayer that are released from
cells of the cardiovascular system, and are considered important mediators of intercellular …

Methods for the physical characterization and quantification of extracellular vesicles in biological samples

DLM Rupert, V Claudio, C Lässer, M Bally - Biochimica et Biophysica Acta …, 2017 - Elsevier
Background Our body fluids contain a multitude of cell-derived vesicles, secreted by most
cell types, commonly referred to as extracellular vesicles. They have attracted considerable …

Extracellular vesicles as tools and targets in therapy for diseases

MA Kumar, SK Baba, HQ Sadida… - Signal transduction and …, 2024 - nature.com
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …

Extracellular vesicle release and uptake by the liver under normo-and hyperlipidemia

K Németh, Z Varga, D Lenzinger, T Visnovitz… - Cellular and Molecular …, 2021 - Springer
Liver plays a central role in elimination of circulating extracellular vesicles (EVs), and it also
significantly contributes to EV release. However, the involvement of the different liver cell …

Intercellular communication between hepatic cells in liver diseases

K Sato, L Kennedy, S Liangpunsakul… - International journal of …, 2019 - mdpi.com
Liver diseases are perpetuated by the orchestration of hepatocytes and other hepatic non-
parenchymal cells. These cells communicate and regulate with each other by secreting …

Extracellular vesicles as potential biomarkers and therapeutic approaches in autoimmune diseases

K Xu, Q Liu, K Wu, L Liu, M Zhao, H Yang… - Journal of Translational …, 2020 - Springer
Extracellular vesicles are heterogeneous populations of naturally occurring secreted small
vesicles. EVs function as signaling platforms to facilitate intracellular communication, which …

Proteomic profiling of extracellular vesicles reveals additional diagnostic biomarkers for myocardial infarction compared to plasma alone

O Gidlöf, M Evander, M Rezeli, G Marko-Varga… - Scientific reports, 2019 - nature.com
Extracellular vesicles (EVs) are submicron, membrane-enclosed particles that are released
from cells in various pathophysiological states. The molecular cargo of these vesicles is …

Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles

B György, TG Szabó, M Pásztói, Z Pál, P Misják… - Cellular and molecular …, 2011 - Springer
Release of membrane vesicles, a process conserved in both prokaryotes and eukaryotes,
represents an evolutionary link, and suggests essential functions of a dynamic extracellular …

Extracellular vesicles in renal diseases: more than novel biomarkers?

U Erdbrügger, TH Le - Journal of the American Society of …, 2016 - journals.lww.com
Extracellular vesicles from the urine and circulation have gained significant interest as
potential diagnostic biomarkers in renal diseases. Urinary extracellular vesicles contain …

Extracellular vesicles: potential applications in cancer diagnosis, prognosis, and epidemiology

M Verma, TK Lam, E Hebert, RL Divi - BMC clinical pathology, 2015 - Springer
Both normal and diseased cells continuously shed extracellular vesicles (EVs) into
extracellular space, and the EVs carry molecular signatures and effectors of both health and …