Unconventional RNA‐binding proteins step into the virus–host battlefront

M Garcia‐Moreno, AI Järvelin… - Wiley Interdisciplinary …, 2018 - Wiley Online Library
The crucial participation of cellular RNA‐binding proteins (RBPs) in virtually all steps of virus
infection has been known for decades. However, most of the studies characterizing this …

Advances in the characterization of RNA‐binding proteins

D Marchese, NS de Groot… - Wiley …, 2016 - Wiley Online Library
From transcription, to transport, storage, and translation, RNA depends on association with
different RNA‐binding proteins (RBPs). Methods based on next‐generation sequencing and …

RNA binding proteins as pioneer determinants of infection: protective, proviral, or both?

S Lisy, K Rothamel, M Ascano - Viruses, 2021 - mdpi.com
As the first intracellular host factors that directly interact with the genomes of RNA viruses,
RNA binding proteins (RBPs) have a profound impact on the outcome of an infection …

Classification and function of RNA–protein interactions

S Liu, B Li, Q Liang, A Liu, L Qu… - Wiley Interdisciplinary …, 2020 - Wiley Online Library
Almost all RNAs need to interact with proteins to fully exert their functions, and proteins also
bind to RNAs to act as regulators. It has now become clear that RNA–protein interactions …

A brave new world of RNA-binding proteins

MW Hentze, A Castello, T Schwarzl… - Nature reviews Molecular …, 2018 - nature.com
RNA-binding proteins (RBPs) are typically thought of as proteins that bind RNA through one
or multiple globular RNA-binding domains (RBDs) and change the fate or function of the …

Uncovering viral RNA–host cell interactions on a proteome-wide scale

L Iselin, N Palmalux, W Kamel, P Simmonds… - Trends in biochemical …, 2022 - cell.com
RNA viruses interact with a wide range of cellular RNA-binding proteins (RBPs) during their
life cycle. The prevalence of these host–virus interactions has been highlighted by new …

From parts lists to functional significance—RNA–protein interactions in gene regulation

C Kilchert, K Sträßer, V Kunetsky… - Wiley Interdisciplinary …, 2020 - Wiley Online Library
Hundreds of canonical RNA binding proteins facilitate diverse and essential RNA
processing steps in cells forming a central regulatory point in gene expression. However …

RBP2GO: a comprehensive pan-species database on RNA-binding proteins, their interactions and functions

M Caudron-Herger, RE Jansen, E Wassmer… - Nucleic acids …, 2021 - academic.oup.com
RNA–protein complexes have emerged as central players in numerous key cellular
processes with significant relevance in health and disease. To further deepen our …

Roadblocks and fast tracks: how RNA binding proteins affect the viral RNA journey in the cell

E Girardi, S Pfeffer, TF Baumert, K Majzoub - Seminars in cell & …, 2021 - Elsevier
As obligate intracellular parasites with limited coding capacity, RNA viruses rely on host
cells to complete their multiplication cycle. Viral RNAs (vRNAs) are central to infection. They …

RNA–protein interactions

KB Hall - Current opinion in structural biology, 2002 - Elsevier
Recent discoveries have revealed that there is a myriad of RNAs and associated RNA-
binding proteins that spatially and temporally appear in the cells of all organisms. The …