Systems and synthetic biology to elucidate secondary metabolite biosynthetic gene clusters encoded in Streptomyces genomes
Covering: 2010 to 2020 Over the last few decades, Streptomyces have been extensively
investigated for their ability to produce diverse bioactive secondary metabolites. Recent …
investigated for their ability to produce diverse bioactive secondary metabolites. Recent …
The re-emerging role of microbial natural products in antibiotic discovery
O Genilloud - Antonie Van Leeuwenhoek, 2014 - Springer
New classes of antibacterial compounds are urgently needed to respond to the high
frequency of occurrence of resistances to all major classes of known antibiotics. Microbial …
frequency of occurrence of resistances to all major classes of known antibiotics. Microbial …
[HTML][HTML] The extremophilic actinobacteria: from microbes to medicine
Actinobacteria constitute prolific sources of novel and vital bioactive metabolites for
pharmaceutical utilization. In recent years, research has focused on exploring actinobacteria …
pharmaceutical utilization. In recent years, research has focused on exploring actinobacteria …
Exploitation of the Streptomyces coelicolor A3(2) genome sequence for discovery of new natural products and biosynthetic pathways
GL Challis - Journal of industrial microbiology and …, 2014 - academic.oup.com
Streptomyces, and related genera of Actinobacteria, are renowned for their ability to produce
antibiotics and other bioactive natural products with a wide range of applications in medicine …
antibiotics and other bioactive natural products with a wide range of applications in medicine …
Strain improvement in actinomycetes in the postgenomic era
RH Baltz - Journal of industrial microbiology and Biotechnology, 2011 - academic.oup.com
With the recent advances in DNA sequencing technologies, it is now feasible to sequence
multiple actinomycete genomes rapidly and inexpensively. An important observation that …
multiple actinomycete genomes rapidly and inexpensively. An important observation that …