Ethanol shares with all major dependence producing drugs the ability to activate brain
mesocorticolimbic dopamine neurons, an important part of the brain reward systems. This …

Ethanol and nicotine are the most abused drugs, and it is well known that co-abuse of
ethanol and nicotine is frequent in human beings. We have previously obtained results …

The most commonly abused drugs, alcohol and nicotine, are likely also the most costly
drugs in terms of health and societal costs. A large body of evidence from epidemiological …

It has been suggested that the mesolimbic dopamine activating and the reinforcing
properties of ethanol involve activation of central nicotinic acetylcholine receptors. To test …

Alcoholism is a chronic recurring brain disorder causing the afflicted a multitude of social
and health problems and enormous costs to society. The psychosocial and pharmacological …

Aims: Concurrent use of ethanol and nicotine (tobacco) is often seen in human beings. In
previous animal experiments, we have demonstrated that nicotinic acetylcholine receptors …

1. Alcohol is one of the most widely used recreational drugs, but also one of the most widely
abused, causing vast economic, social and personal damage. 2. 2. Several animal models …

The brain reward system, and especially the mesolimbic dopamine pathway, plays a major
role in drug reinforcement and is most likely involved in the development of drug addiction …

Ethanol-induced elevations of accumbal dopamine levels have been linked to the
reinforcing properties of the drug. However, it has not yet been demonstrated where the …

It has been suggested that ethanol exerts its mesolimbic dopamine activating effects and its
reinforcing effects via interaction with central nicotinic acetylcholine receptors, thus providing …