Toll-like Receptors (TLR) are phylogenetically conserved transmembrane proteins
responsible for detection of pathogens and activation of immune responses in diverse …

Toll-like receptors (TLRs) are the archetypal pattern recognition receptors in sensing
exogenous pathogens. Activation of TLRs is a first line of defense of the immune system …

The Toll-like receptors (TLRs) are a family of pathogen recognition receptors that alert the
host to the presence of microbial challenge. Each TLR responds to a specific microbial …

The innate immune response is a first-line defense system in which individual Toll-like
receptors (TLRs) recognize distinct pathogen-associated molecular patterns (PAMPs) and …

Toll-like receptors (TLRs) are important sensors of foreign microbial components as well as
products of damaged or inflamed self tissues. Upon sensing these molecules, TLRs initiate a …

Toll-like receptors (TLRs) are involved in host defence against invading pathogens,
functioning as primary sensors of microbial products and activating signalling pathways that …

Toll-like receptors (TLRs) are pivotal components of the innate immune response, which is
responsible for eradicating invading microorganisms through the induction of inflammatory …

Toll‐like receptors (TLRs) are critical pattern recognition receptors (PRRs) that recognize
pathogen‐associated molecular patterns (PAMPs), which are conserved and specific …

Recognition of pathogens by toll-like receptors (TLRs) causes activation of signaling
cascades that trigger cytokine secretion and, ultimately, innate immunity. Genes encoding …

Toll-like receptor (TLR) signaling is subjected to crosstalk from other signals, with a resulting
positive or negative effect. There is complex crosstalk between the NLR family of immune …