Functional connectivity (FC) analyses of resting-state fMRI data allow for the mapping of
large-scale functional networks, and provide a novel means of examining the impact of …

Dopamine underlies important aspects of cognition, and has been suggested to boost
cognitive performance. However, how dopamine modulates the large-scale cortical …

Parkinson's disease (PD) is a progressive neurodegenerative disorder that is characterized
by dopamine depletion in the striatum. One consistent pathophysiological hallmark of PD is …

Dopamine depletion in the putamen is associated with altered motor network functional
connectivity in people with Parkinson's disease (PD), but the functional significance of these …

Dopaminergic projections are hypothesized to stabilize neural signaling and neural
representations, but how they shape regional information processing and large-scale …

Patients with idiopathic Parkinson's disease suffer not only from classic motor symptoms, but
from deficits in cognitive function, primarily those subserved by the prefrontal cortex as well …

This study examined the effects of l‐dopa medication in patients with Parkinson's disease on
cortical and subcortical blood flow changes during two tasks known to involve frontostriatal …

The pathological hallmark of Parkinson's disease is the degeneration of dopaminergic
nigrostriatal neurons, leading to depletion of striatal dopamine. Recent neuroanatomical …

Openness is a personality trait reflecting absorption in sensory experience, preference for
novelty, and creativity, and is thus considered a driving force of human evolution. At the …

Dopaminergic medications, used to treat neurochemical pathology and resultant symptoms
in neuropsychiatric disorders, are of mixed efficacy and regularly associated with …