Biological therapies in inflammatory bowel disease: Beyond anti-TNF therapies

KH Katsanos, K Papamichael, JD Feuerstein… - Clinical …, 2019 - Elsevier
The pharmacological management of inflammatory bowel disease (IBD) over the last two
decades has transitioned from reliance on aminosalycilates, corticosteroids and …

Innovations in oral therapies for inflammatory bowel disease

C Ma, R Battat, PS Dulai, CE Parker, WJ Sandborn… - Drugs, 2019 - Springer
Prior to the biologic era, the medical management of patients with inflammatory bowel
disease (IBD) was dominated by the use of aminosalicylates, corticosteroids, and …

Novel therapeutic targets for inflammatory bowel disease

M Argollo, G Fiorino, P Hindryckx, L Peyrin-Biroulet… - Journal of …, 2017 - Elsevier
Inflammatory bowel disease (IBD), including Crohn's disease (CD) and Ulcerative Colitis
(UC), are immune mediated conditions associated with progressive damage of the inflamed …

[HTML][HTML] Inflammatory pathways of importance for management of inflammatory bowel disease

J Pedersen, M Coskun, C Soendergaard… - World journal of …, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD) is a group of chronic disorders of the gastrointestinal tract
comprising Crohn's disease (CD) and ulcerative colitis (UC). Their etiologies are unknown …

IBD disease-modifying therapies: insights from emerging therapeutics

NG Kotla, Y Rochev - Trends in Molecular Medicine, 2023 - cell.com
Inflammatory bowel disease (IBD) pathogenesis is associated with gut mucosal
inflammation, epithelial damage, and dysbiosis leading to a dysregulated gut mucosal …

Overcoming therapeutic obstacles in inflammatory bowel diseases: a comprehensive review on novel drug delivery strategies

F Talaei, F Atyabi, M Azhdarzadeh, R Dinarvand… - European Journal of …, 2013 - Elsevier
Inflammatory bowel diseases (IBDs) are a group of debilitating inflammatory complications
specially inflicting colonic tissue in which full long term remission with current standardized …

[HTML][HTML] The innate and adaptive immune system as targets for biologic therapies in inflammatory bowel disease

G Holleran, L Lopetuso, V Petito, C Graziani… - International journal of …, 2017 - mdpi.com
Inflammatory bowel disease (IBD) is an immune-mediated inflammatory condition causing
inflammation of gastrointestinal and systemic cells, with an increasing prevalence …

Inflammatory bowel disease therapeutics: A focus on probiotic engineering

J Mishra, M Stubbs, L Kuang, N Vara… - Mediators of …, 2022 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of gastrointestinal (GI)
tract with dysregulated mucosal immune functions and disturbed commensal ecosystem of …

Biologic therapy of inflammatory bowel disease

WJ Sandborn, SR Targan - Gastroenterology, 2002 - Elsevier
Advancing knowledge regarding the biology of chronic inflammation has led to the
development of specific biologic therapies that mechanistically target individual …

Medical therapy of inflammatory bowel disease for the 21st century

M Robinson - European Journal of Surgery, 1998 - academic.oup.com
Inflammatory bowel disease therapy can be considered in several subcategories, and this
review is designed to provide selective updates for some of the most important therapeutic …