Gold (III) complexes as potential antitumor agents: solution chemistry and cytotoxic properties of some selected gold (III) compounds
Gold (III) complexes generally exhibit interesting cytotoxic and antitumor properties, but until
now, their development has been heavily hampered by their poor stability under …
now, their development has been heavily hampered by their poor stability under …
[PDF][PDF] Gold (III) compounds as new family of anticancer drugs
Gold (III) complexes are emerging asa new class of metal complexes with outstanding
cytotoxic properties and are presently being evaluated as potential antitumor agents. This …
cytotoxic properties and are presently being evaluated as potential antitumor agents. This …
Antitumor properties of some 2-[(dimethylamino) methyl] phenylgold (III) complexes
RG Buckley, AM Elsome, SP Fricker… - Journal of medicinal …, 1996 - ACS Publications
Four analogues of the gold (III) complex [AuCl2 (damp)](1)(damp= 2-[(dimethylamino)
methyl] phenyl) have been evaluated for antitumor activity. The compounds have structural …
methyl] phenyl) have been evaluated for antitumor activity. The compounds have structural …
Synthesis, structural characterization, solution behavior, and in vitro antiproliferative properties of a series of gold complexes with 2-(2′-pyridyl) benzimidazole as …
A variety of gold (III) and gold (I) derivatives of 2-(2′-pyridyl) benzimidazole (pbiH) were
synthesized and fully characterized and their antiproliferative properties evaluated in a …
synthesized and fully characterized and their antiproliferative properties evaluated in a …
Gold (III) compounds as anticancer drugs
Gold (III) complexes constitute a new class of metallodrugs, of potential interest for cancer
treatment. During the past decade different kinds of gold (III) complexes have been reported …
treatment. During the past decade different kinds of gold (III) complexes have been reported …
Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold (III) compounds for cancer treatment: a systematic study
The antiproliferative properties of a group of 13 structurally diverse gold (III) compounds,
including six mononuclear gold (III) complexes, five dinuclear oxo-bridged gold (III) …
including six mononuclear gold (III) complexes, five dinuclear oxo-bridged gold (III) …
Gold coordination complexes as anticancer agents.
I Kostova - Anti-cancer agents in medicinal chemistry, 2006 - europepmc.org
Metal ions are known to bind with nucleic acids and thereby alter their conformation and
biological function. The metal ion-base interaction depends on the nature of both metal and …
biological function. The metal ion-base interaction depends on the nature of both metal and …
Gold (III) complexes with bipyridyl ligands: solution chemistry, cytotoxicity, and DNA binding properties
G Marcon, S Carotti, M Coronnello… - Journal of Medicinal …, 2002 - ACS Publications
Gold (III) compounds generally exhibit significant cytotoxic effects on cancer cell lines and
are of potential interest as antitumor drugs. We report here on the solution chemistry, the …
are of potential interest as antitumor drugs. We report here on the solution chemistry, the …
Correlation of the in vitro cytotoxic and in vivo antitumor activities of gold (I) coordination complexes
CK Mirabell, RK Johnson, DT Hill… - Journal of medicinal …, 1986 - ACS Publications
Method A.[2, 3, 4, 6-Tetrakis-0-[(methylamino)-carbonyl]-l-thio-/JD-glucopyranosato-
S](triethyl-phosphine) gold (3). A mixture of 2 (5.2 g, 0.01 mol) and methyl isocyanate (100 g …
S](triethyl-phosphine) gold (3). A mixture of 2 (5.2 g, 0.01 mol) and methyl isocyanate (100 g …
Chemical biology of anticancer gold (III) and gold (I) complexes
T Zou, CT Lum, CN Lok, JJ Zhang… - Chemical Society Reviews, 2015 - pubs.rsc.org
Gold complexes have recently gained increasing attention in the design of new metal-based
anticancer therapeutics. Gold (III) complexes are generally reactive/unstable under …
anticancer therapeutics. Gold (III) complexes are generally reactive/unstable under …