Diabetes mellitus related biomarker: the predictive role of growth-differentiation factor-15

AE Berezin - Diabetes & Metabolic Syndrome: Clinical Research & …, 2016 - Elsevier
Abstract Growth differentiation factor-15 (GDF-15) is a stress-responsive cytokine, which
belongs to super family of the transforming growth factor beta. GDF-15 is widely presented in …

Growth differentiation factor-15 and its role in diabetes and cardiovascular disease

AC Eddy, AJ Trask - Cytokine & growth factor reviews, 2021 - Elsevier
Abstract Growth differentiation factor-15 (GDF-15) is cytokine involved in the regulation of
multiple systems. Because it has regularly been shown to be increased in cardiovascular …

GDF15 is a novel biomarker for impaired fasting glucose

JH Hong, HK Chung, HY Park… - Diabetes & …, 2014 - synapse.koreamed.org
Background Growth differentiation factor-15 (GDF15) is a protein that belongs to the
transforming growth factor β superfamily. An elevated serum level of GDF15 was found to be …

GDF‐15 as a target and biomarker for diabetes and cardiovascular diseases: a translational prospective

R Adela, SK Banerjee - Journal of diabetes research, 2015 - Wiley Online Library
Growth differentiation factor‐15 (GDF‐15) is a stress responsive cytokine. It is highly
expressed in cardiomyocytes, adipocytes, macrophages, endothelial cells, and vascular …

Association between growth differentiation factor 15 (GDF15) and cardiovascular risk in patients with newly diagnosed type 2 diabetes mellitus

MY Shin, JM Kim, YE Kang, MK Kim… - Journal of Korean …, 2016 - synapse.koreamed.org
We investigated an association between serum Growth Differentiation Factor 15 (GDF15)
level and cardiovascular risk in patients with newly diagnosed type 2 diabetes mellitus …

GDF15 reflects beta cell function in obese patients independently of the grade of impairment of glucose metabolism

MH Schernthaner-Reiter, BK Itariu, M Krebs… - Nutrition, Metabolism …, 2019 - Elsevier
Background and aims Growth differentiation factor 15 (GDF15) is a strong predictor of
cardiovascular morbidity and mortality found to be both marker and target of impaired …

Growth differentiation factor 15 predicts future insulin resistance and impaired glucose control in obese nondiabetic individuals: results from the XENDOS trial

T Kempf, A Guba-Quint, J Torgerson… - European Journal of …, 2012 - academic.oup.com
Objective Growth differentiation factor-15 (GDF-15) is a stress-responsive cytokine that is
increased in obesity and established type 2 diabetes. We assessed whether GDF-15 can …

The relationship between insulin resistance and the cardiovascular biomarker growth differentiation factor-15 in obese patients

G Vila, M Riedl, C Anderwald, M Resl… - Clinical …, 2011 - academic.oup.com
BACKGROUND Growth differentiation factor-15 (GDF-15) is a stress-responsive cytokine
linked to obesity comorbidities such as cardiovascular disease, inflammation, and cancer …

Increased serum GDF15 related to improvement in metabolism by lifestyle intervention among young overweight and obese adults

L Cai, C Li, Y Wang, Y Mo, J Yin… - … , Metabolic Syndrome and …, 2021 - Taylor & Francis
Aim Growth differentiation factor 15 (GDF15) is closely related to obesity. This study aimed to
explore the influence of weight loss intervention on serum GDF15 levels and the relationship …

Metformin is the key factor in elevated plasma growth differentiation factor‐15 levels in type 2 diabetes: A nested, case–control study

A Natali, L Nesti, E Venturi, AC Shore… - Diabetes, Obesity …, 2019 - Wiley Online Library
Produced as a tissue defence response to hypoxia and inflammation, growth differentiation
factor‐15 (GDF‐15) is elevated in people receiving metformin treatment. To gain insight into …