Effect of grape seed proanthocyanidins on colon aberrant crypts and breast tumors in a rat dual-organ tumor model

KW Singletary, B Meline - Nutrition and cancer, 2001 - Taylor & Francis
Cancers of the colon and breast are two of the most prevalent cancers in developed
countries. The present experiments were conducted to determine the influence of several …

Dietary administration with prenyloxycoumarins, auraptene and collinin, inhibits colitis‐related colon carcinogenesis in mice

H Kohno, R Suzuki, M Curini, F Epifano… - … journal of cancer, 2006 - Wiley Online Library
We previously reported the chemopreventive ability of a prenyloxycoumarin auraptene in
chemically induced carcinogenesis in digestive tract, liver and urinary bladder of rodents …

Suppression of azoxymethane‐induced colon carcinogenesis in male F344 rats by mandarin juices rich in β‐cryptoxanthin and hesperidin

T Tanaka, H Kohno, M Murakami… - … Journal of Cancer, 2000 - Wiley Online Library
We have reported protective effects of dietary administration of a powder “CHRP” containing
high amounts of β‐cryptoxanthin and hesperidin prepared from a Satsuma mandarin (Citrus …

Modulating effects of ellagic acid, vanillin and quercetin in a rat medium term multi-organ carcinogenesis model

K Akagi, M Hirose, T Hoshiya, Y Mizoguchi, N Ito… - Cancer letters, 1995 - Elsevier
Effects of dietary supplementation with the antioxidants ellagic acid, quercetin and vanillin
were examined using a medium term multi-organ carcinogenesis model in rats. Groups of …

Chemopreventive effects of carotenoids and curcumins on mouse colon carcinogenesis after 1, 2-dimethylhydrazine initiation.

JM Kim, S Araki, DJ Kim, CB Park, N Takasuka… - …, 1998 - academic.oup.com
The present study was carried out to examine the chemopreventive effects of carotenoids
such as fucoxanthin, lycopene and lutein as well as curcumin and its derivative …

Enhancement of experimental colon cancer by genistein

CV Rao, CX Wang, B Simi, R Lubet, G Kelloff, V Steele… - Cancer research, 1997 - AACR
Several phytochemicals and micronutrients that are present in fruits and vegetables are
known to exert cancer chemopreventive effects in several organs, including the colon …

Prevention of colonic aberrant crypt foci by dietary feeding of garcinol in male F344 rats

T Tanaka, H Kohno, R Shimada, S Kagami… - …, 2000 - academic.oup.com
The modifying effects of dietary feeding of a polyisoprenylated benzophenone, garcinol,
isolated from Garcinia indica fruit rind on the development of azoxymethane (AOM)-induced …

Modulation of apoptosis by sulindac, curcumin, phenylethyl-3-methylcaffeate, and 6-phenylhexyl isothiocyanate: apoptotic index as a biomarker in colon cancer …

HS Samaha, GJ Kelloff, V Steele, CV Rao, BS Reddy - Cancer research, 1997 - AACR
Recent evidence supports the theory that tumor growth in vivo depends on evasion of
normal homeostatic control mechanisms that operate through induction of cell death by …

Chemopreventive effect of trans -resveratrol - a phytoalexin against colonic aberrant crypt foci and cell proliferation in 1,2-dimethylhydrazine induced …

M Sengottuvelan, P Viswanathan, N Nalini - Carcinogenesis, 2006 - academic.oup.com
Prevention of cancer remains a primary need and new chemopreventive agents must be
developed for this purpose. Towards this goal, a chemoprevention study was conducted to …

Chemoprevention of colon carcinogenesis by the natural product of a simple phenolic compound protocatechuic acid: suppressing effects on tumor development and …

T Tanaka, T Kojima, M Suzui, H Mori - Cancer research, 1993 - AACR
Our previous study has shown that dietary administration of protocatechuic acid (PCA) acts
as potential chemopreventive agent in inhibiting diethylnitrosamine-induced liver …