Colorectal cancer (CRC) is the second most fatal and the third most diagnosed type of
cancer worldwide. Despite having multifactorial causes, most CRC cases are mainly …

Purpose. Recent preclinical assays using animal models have shown that naturally-
occurring and synthetic chemicals such as auraptene (AUR), nobiletin (NOB), hesperidin …

This perspective describes some commonly used animal models for the evaluation of
potential chemopreventive agents in colon carcinogenesis. Special emphasis is given to the …

Intestinal neoplasia (adenomas and carcinomas) can possibly be prevented by a diet rich in
vegetables and fruits, treatment with aspirin and other nonsteroidal antiinflammatory drugs …

To shed light on colon cancer chemoprevention, natural phytochemicals attract researchers
by virtue of their beneficial biological effects. The chemopreventive potential of rosmarinic …

Abstract 1, 2 Dimethyl hydrazine (DMH), a cogent environmental toxicant, targets the colon.
Previous reports suggest that DMH‐mediated dysregulation of the Wnt/β‐catenin pathway …

We investigated whether resveratrol (RV) affects azoxymethane (AOM)-induced colon
carcinogenesis, by administering RV (200 μg/kg/day in drinking water) to male F344 rats for …

In our studies to find natural compounds with chemopreventive efficacy in foods, using
azoxymethane (AOM)‐induced colonic aberrant crypt foci and colonic mucosal cell …

Background: Colorectal cancer is the main leading cause of cancer-related deaths
worldwide. Present data suggest that plant-derived anthocyanins have anti-inflammatory …

We have previously demonstrated that ursodeoxycholic acid (UDCA) and a fluorinated
analogue of vitamin D3, F6-D3, inhibited colonic carcinogenesis in the azoxymethane …