Baseline cardiac parameters as biomarkers of radiation cardiotoxicity in lung cancer: an NI-HEART analysis
GM Walls, N Hill, M McMahon, B Kearney, C McCann… - Cardio Oncology, 2024 - jacc.org
Background Radiation-induced cardiotoxicity poses a significant challenge in lung cancer
management because of the close anatomical proximity of the heart to the lungs …
management because of the close anatomical proximity of the heart to the lungs …
Cardiac radiation dose, cardiac disease, and mortality in patients with lung cancer
KM Atkins, B Rawal, TL Chaunzwa, N Lamba… - Journal of the American …, 2019 - jacc.org
Background: Radiotherapy-associated cardiac toxicity studies in patients with locally
advanced non–small cell lung cancer (NSCLC) have been limited by small sample size and …
advanced non–small cell lung cancer (NSCLC) have been limited by small sample size and …
Dosimetric predictors of cardiotoxicity in thoracic radiotherapy for lung cancer
JF Borkenhagen, C Bergom, CT Rapp… - Clinical Lung Cancer, 2019 - Elsevier
Background Higher cardiac radiotherapy (RT) doses when treating lung cancer are
associated with worse overall survival (OS), although the direct association between cardiac …
associated with worse overall survival (OS), although the direct association between cardiac …
The association of incidental radiation dose to the heart base with overall survival and cardiac events after curative-intent radiotherapy for non-small cell lung cancer …
GM Walls, J O'Connor, M Harbinson, F Duane… - Clinical Oncology, 2024 - Elsevier
Aims Cardiac disease is a dose-limiting toxicity in non-small cell lung cancer radiotherapy.
The dose to the heart base has been associated with poor survival in multiple institutional …
The dose to the heart base has been associated with poor survival in multiple institutional …
Heart dosimetric analysis of three types of cardiac toxicity in patients treated on dose-escalation trials for Stage III non-small-cell lung cancer
K Wang, KA Pearlstein, ND Patchett, AM Deal… - Radiotherapy and …, 2017 - Elsevier
Background and purpose To assess associations between radiation dose/volume
parameters for cardiac subvolumes and different types of cardiac events in patients treated …
parameters for cardiac subvolumes and different types of cardiac events in patients treated …
Predicting adverse cardiac events after radiotherapy for locally advanced non–small cell lung cancer
Background Radiotherapy may cause grade≥ 3 cardiac events, necessitating a better
understanding of risk factors. The potential predictive role of imaging biomarkers with …
understanding of risk factors. The potential predictive role of imaging biomarkers with …
Cardiac morbidity following chemoradiation in stage III non-small cell lung cancer patients: a population-based cohort study
EK Donovan, GR Pond, H Seow, PM Ellis… - Clinical Oncology, 2023 - Elsevier
Aims To assess the risk of cardiac toxicity following radical radiotherapy in advanced lung
cancer patients. Materials and methods Patients with a diagnosis of stage III non-small cell …
cancer patients. Materials and methods Patients with a diagnosis of stage III non-small cell …
Predicting Radiation-Induced Heart Disease and Survival—Is Location the Key?
More than half of all patients with cancer receive radiation therapy. While radiation is a
critical component of cancer treatment for many malignancies, incidental cardiac radiation …
critical component of cancer treatment for many malignancies, incidental cardiac radiation …
[HTML][HTML] Prediction models for treatment-induced cardiac toxicity in patients with non-small-cell lung cancer: A systematic review and meta-analysis
F Tohidinezhad, F Pennetta, J van Loon… - Clinical and …, 2022 - Elsevier
Background To maximize the likelihood of positive outcome in non-small-cell lung cancer
(NSCLC) survivors, potential benefits of treatment modalities have to be weighed against the …
(NSCLC) survivors, potential benefits of treatment modalities have to be weighed against the …
[HTML][HTML] Prospective exploratory analysis of cardiac biomarkers and electrocardiogram abnormalities in patients receiving thoracic radiation therapy with high-dose …
DR Gomez, SW Yusuf, MF Munsell, JW Welsh… - Journal of Thoracic …, 2014 - Elsevier
Introduction Acute effects of incidental cardiac irradiation in patients treated for thoracic
cancer are not well characterized. We evaluated longitudinal changes in cardiac biomarkers …
cancer are not well characterized. We evaluated longitudinal changes in cardiac biomarkers …