Retinal ischemia-reperfusion (I/R) is a pathophysiological process contributing to cellular
damage in multiple ocular conditions, including glaucoma, diabetic retinopathy, and retinal …

Retinal ischemia/reperfusion (I/R) injury is an important cause of visual impairment.
However, questions remain on the overall I/R mechanisms responsible for progressive …

Research has been conducted into vascular abnormalities in the pathogenesis of glaucoma,
but conclusions remain controversial. Our aim was to test the hypothesis that retinal …

Retinal ischemia is a common pathomechanism in many ocular disorders such as age-
related macular degeneration (AMD), diabetic retinopathy, glaucoma or retinal vascular …

Increased intraocular pressure and vascular ligation models are often used in studies of
global ocular ischemia. The purpose of this study is to perform a paired comparison of retinal …

Retinal ischemia is a major cause of blindness worldwide. It is associated with various
disorders such as diabetic retinopathy, glaucoma, optic neuropathies, stroke, and other …

Objectives Much of our knowledge of the pathophysiology of retinal ischemic injury is from a
multitude of studies that use in vitro or in vivo animal models of retinal ischemia followed by …

Retina, one of the highest oxygen demanding tissues, is vulnerable to vascular
insufficiencies, and various ocular vascular disorders can cause chronic retinal ischemia. To …

purpose. Retinal neurons and vasculature interact with each other under normal conditions,
and occlusion of the retinal vasculature can result in damage to retinal neurons. Whether …

Background Several retinal pathologies exhibit both inflammation and breakdown of the
inner blood-retinal barrier (iBRB) resulting in vascular permeability, suggesting that …