Maternal and placental DNA methylation changes associated with the pathogenesis of gestational diabetes mellitus

P Xu, S Dong, L Wu, Y Bai, X Bi, Y Li, C Shu - Nutrients, 2022 - mdpi.com
Gestational diabetes mellitus (GDM) is an important metabolic complication of pregnancy,
which affects the future health of both the mother and the newborn. The pathogenesis of …

DNA methylation profiles in placenta and its association with gestational diabetes mellitus

C Rong, X Cui, J Chen, Y Qian, R Jia… - … Clinical Endocrinology & …, 2015 - thieme-connect.com
Emerging evidences indicate that placenta plays a critical role in gestational diabetes
mellitus (GDM). DNA methylation could be associated with altered placental development …

The role of maternal DNA methylation in pregnancies complicated by gestational diabetes

S Dias, T Willmer, S Adam, C Pheiffer - Frontiers in Clinical Diabetes …, 2022 - frontiersin.org
Diabetes in pregnancy is associated with adverse pregnancy outcomes and poses a serious
threat to the health of mother and child. Although the pathophysiological mechanisms that …

[HTML][HTML] Deciphering DNA Methylation in Gestational Diabetes Mellitus: Epigenetic Regulation and Potential Clinical Applications

N Li, HY Liu, SM Liu - International Journal of Molecular Sciences, 2024 - mdpi.com
Gestational diabetes mellitus (GDM) represents a prevalent complication during pregnancy,
exerting both short-term and long-term impacts on maternal and offspring health. This review …

Gestational diabetes mellitus alters DNA methylation profiles in pancreas of the offspring mice

Z Zhu, X Chen, Y Xiao, J Wen, J Chen, K Wang… - Journal of Diabetes and …, 2019 - Elsevier
Gestational diabetes mellitus (GDM), which has an increasing global prevalence,
contributes to the susceptibility to metabolic dysregulation and obesity in the offspring via …

Genome-wide DNA methylation variation in maternal and cord blood of gestational diabetes population

J Kang, CN Lee, HY Li, KH Hsu, SY Lin - Diabetes research and clinical …, 2017 - Elsevier
Aims Gestational diabetes mellitus (GDM) has always been a concerning issue for pregnant
women. In recent studies, GDM was found to be related to epigenetic modifications, which …

Epigenetic changes in gestational diabetes mellitus

DF Dłuski, E Wolińska, M Skrzypczak - International Journal of Molecular …, 2021 - mdpi.com
Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance that appears or
is for the first time diagnosed during pregnancy. It can lead to many complications in the …

The placenta as a target of epigenetic alterations in women with gestational diabetes mellitus and potential implications for the offspring

D Lizárraga, A García-Gasca - Epigenomes, 2021 - mdpi.com
Gestational diabetes mellitus (GDM) is a pregnancy complication first detected in the second
or third trimester in women that did not show evident glucose intolerance or diabetes before …

Increased global placental DNA methylation levels are associated with gestational diabetes

C Reichetzeder, SE Dwi Putra, T Pfab, T Slowinski… - Clinical …, 2016 - Springer
Background Gestational diabetes mellitus (GDM) is associated with adverse pregnancy
outcomes. It is known that GDM is associated with an altered placental function and changes …

Placental maternally expressed gene 3 differentially methylated region methylation profile is associated with maternal glucose concentration and newborn birthweight

C Chen, Y Jiang, T Yan, Y Chen… - Journal of Diabetes …, 2021 - Wiley Online Library
Abstract Aims/Introduction Emerging evidence shows that epigenetic modifications occurring
during fetal development in response to intrauterine exposures could be one of the …