Emerging research highlights the complex interrelationships between sleep-disordered
breathing and cardiovascular disease, presenting clinical and research opportunities as well …

Synchronization of molecular, metabolic, and cardiovascular circadian oscillations is
fundamental to human health. Sleep-disordered breathing, which disrupts such temporal …

Sleep apnea is highly prevalent in patients with cardiovascular disease. These disordered
breathing events are associated with a profile of perturbations that include intermittent …

Sleep apnea occurs in 5% to 10% of the general population, regardless of race and
ethnicity. 1 By contrast, in patients with cardiovascular diseases (CVDs), its prevalence …

Background It remains uncertain whether continuous positive airway pressure (CPAP)
therapy would significantly impact hard clinical outcomes in patients with obstructive sleep …

Considerable progress has been made regarding the interactions between sleep and
cardiovascular diseases1–3. Historically, a number of abnormalities have been linked with …

The normal sleep-wake cycle is characterized by diurnal variations in blood pressure, heart
rate, and cardiac events. Sleep apnea disrupts the normal sleep-heart interaction, and the …

Patients with a wide variety of cardiovascular diseases, including arterial and pulmonary
hypertension, arrhythmia, coronary artery disease and heart failure, are more likely to report …

Compelling data demonstrate a strong association between sleep-disordered breathing
(SDB) and cardiovascular disorders. The association is most consistent between obstructive …

Cardiovascular disease has been the leading cause of death since 1900 every year except
1918 (influenza epidemic), and approximately one-third of all deaths from cardiovascular …