[HTML][HTML] Acute exposure to tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP) causes hepatic inflammation and leads to hepatotoxicity in zebrafish

C Liu, G Su, JP Giesy, RJ Letcher, G Li, I Agrawal… - Scientific reports, 2016 - nature.com
Abstract Tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP) has been frequently detected in
environmental media and has adverse health effect on wildlife and humans. It has been …

Tris (2-chloroethyl) phosphate exerts hepatotoxic impacts on zebrafish by disrupting hypothalamic–pituitary–thyroid and gut–liver axes

D Tian, Y Yu, Y Yu, L Lu, D Tong, W Zhang… - Environmental …, 2023 - ACS Publications
The ubiquitous environmental presence of tris (2-chloroethyl) phosphate (TCEP) poses a
potential threat to animals; however, little is known about its hepatotoxicity. In this study, the …

Tris (1, 3-dichloro-2-propyl) phosphate causes female-biased growth inhibition in zebrafish: Linked with gut microbiota dysbiosis

W Sun, Y Dang, L Dai, C Liu, J Wang, Y Guo, B Fan… - Aquatic Toxicology, 2023 - Elsevier
Abstract Tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP) is ubiquitous in aquatic
environment, but its effect on intestinal health of fish has yet not been investigated. In the …

[HTML][HTML] Induction of lipid metabolism dysfunction, oxidative stress and inflammation response by tris (1-chloro-2-propyl) phosphate in larval/adult zebrafish

J Yan, Z Zhao, M Xia, S Chen, X Wan, A He… - Environment …, 2022 - Elsevier
As an important organophosphate flame retardant, tris (1-chloro-2-propyl) phosphate
(TCPP) is ubiquitous in the environment leading to inevitable human exposure. However …

Oxidative stress, cell cycle arrest, DNA damage and apoptosis in adult zebrafish (Danio rerio) induced by tris (1, 3-dichloro-2-propyl) phosphate

H Chen, P Wang, Z Du, G Wang, S Gao - Aquatic Toxicology, 2018 - Elsevier
Abstract Tris (1, 3-dichloro-2-propyl) phosphate (TDCPP) is an additive flame retardant of
high production volume, and frequently detected in biota and environment. However …

Progression of liver tumor was promoted by tris (1, 3-dichloro-2-propyl) phosphate through the induction of inflammatory responses in krasV12 transgenic zebrafish

S Chen, Y Dang, Z Gong, RJ Letcher, C Liu - Environmental Pollution, 2019 - Elsevier
Abstract Tris (1, 3-dichloro-2-propyl) phosphate (TDCIPP) has been detected in various
environmental media and has been implicated as a weak mutagen or carcinogen, but …

Exploring the underlying molecular mechanism of tri (1, 3-dichloropropyl) phosphate-induced neurodevelopmental toxicity via thyroid hormone disruption in zebrafish …

Y Xu, L Yang, Y Teng, J Li, N Li - Aquatic Toxicology, 2023 - Elsevier
Abstract Tri (1, 3-dichloropropyl) phosphate (TDCPP) is widespread in the environment as a
typical thyroid hormone-disrupting chemical. Here, we aimed to explore the toxicological …

[HTML][HTML] Transcriptomic, proteomic and metabolomic profiling unravel the mechanisms of hepatotoxicity pathway induced by triphenyl phosphate (TPP)

X Wang, F Li, J Liu, C Ji, H Wu - Ecotoxicology and environmental safety, 2020 - Elsevier
Triphenyl phosphate (TPP) has been found in various environmental media and in biota
suggesting widespread human exposure. However, there is still insufficient information on …

[HTML][HTML] TPhP exposure disturbs carbohydrate metabolism, lipid metabolism, and the DNA damage repair system in zebrafish liver

Z Du, Y Zhang, G Wang, J Peng, Z Wang, S Gao - Scientific reports, 2016 - nature.com
Triphenyl phosphate is a high production volume organophosphate flame retardant that has
been detected in multiple environmental media at increasing concentrations. The …

Enhanced bio-concentration of tris (1, 3-dichloro-2-propyl) phosphate in the presence of nano-TiO2 can lead to adverse reproductive outcomes in zebrafish

X Ren, X Zhao, X Duan, Z Fang - Environmental Pollution, 2018 - Elsevier
Interactions between organic toxicants and nano-particles in the aquatic environment may
modify toxicant bioavailability and consequently the toxicant's fate and toxicity. To evaluate …