Recent studies have demonstrated that the expression of miR‐34a is significantly
upregulated and associated with cell apoptosis in pancreatic β‐cell treated with palmitate …

Chronic exposure to high concentrations of stearic acid (C18: 0) can result in β-cell
dysfunction, leading to development of type 2 diabetes. However, the molecular …

The loss of functional β-cell mass in type 2 diabetes (T2D) is associated with molecular
events that include β-cell apoptosis, dysfunction and/or dedifferentiation. MicroRNA miR-184 …

Lipoapoptosis of pancreatic β cells caused by elevated circulating free fatty acids (FFAs) has
now been recognized to be a pivotal factor contributing to β cellular dysfunction and β-mass …

Baicalin (BAI), one major flavonoid from Scutellaria baicalensis, possesses anticancer and
anti‐inflammatory properties. However, the effect of BAI on diabetes mellitus has not been …

Purpose Pancreatic β-cell failure is a central hallmark of the pathogenesis of diabetes
mellitus; however, the molecular basis underlying chronic inflammation-caused β-cell failure …

Diabetes mellitus (DM) is characterized by the elevated blood glucose levels and is
regarded as one of the most threatening diseases worldwide. The dysfunction of pancreatic …

A variety of studies indicate that microRNAs (miRNAs) are involved in diabetes. However,
the direct role of miR-320a in the pathophysiology of pancreatic β cells under diabetes …

Aims/hypothesis Serum stearic acid (C18: 0) is elevated in individuals with hyperlipidaemia
and type 2 diabetes. However, the lipotoxicity induced by increased stearic acid in beta cells …

Autophagy dysfunction plays a critical role in diabetic cardiomyopathy (DCM). MiR-207
regulates the expression of lysosomal-associated membrane protein 2 (LAMP2), an …