Nine healthy male volunteers received single 0.5, 1.0, and 1.5 mg. doses of intravenous
digoxin in a randomized three-way crossover study. Multiple venous blood samples were …

The purpose of this study was to determine if there is a linear relationship between oral
doses of digoxin and various measurements of steady-state digoxin plasma concentration …

About 70 to 80% of an oral dose of digoxin is absorbed, mainly in the proximal part of the
small intestine. The degree of binding to serum albumin is 20 to 30%. Digoxin is extensively …

Normal subjects were given 0.75 mg of intravenous digoxin as a bolus and a 1-hr infusion,
Radio-immunoassayed serum concentrations obtained over 48 hr and urinary excretion …

Low serum digoxin levels were found in 8 institutionalized patients with congestive heart
failure despite daily administration, in standard dosage, of a digoxin preparation for 4 weeks …

Plasma digoxin levels were determined in 6 healthy, young male subjects by
radioimmunoassay. All were given an oral dose of 1.0 mg. of digoxin the first day, followed …

Nine healthy men received 0.5, 1.0, and 1.5 mg digoxin intravenously in random sequence
on occasions separated by at least 4 wk. Digoxin concentrations were measured in serum …

Digoxin serum and urine levels were determined by radioimmunoassay in 6 subjects (4
patients with heart disease and 2 volunteers without heart disease) who had been …

The following summarises the contents of both this review and its predecessor in this journal
(Iisalo, 1977). The two reviews should be read in conjunction with each other. Digoxin is …

Seven healthy volunteers received a single 1.0‐mg dose of intravenous digoxin in a drug‐
free control trial and again during concurrent therapy with therapeutic doses of quinidine …