Bioactive compound 1, 8-Cineole selectively induces G2/M arrest in A431 cells through the upregulation of the p53 signaling pathway and molecular docking studies
S Sampath, S Subramani, S Janardhanam… - Phytomedicine, 2018 - Elsevier
Background Callistemon citrinus has been traditionally known for its medicinal property.
Recently, our research group identified 1, 8-Cineole, as one of the predominant compound …
Recently, our research group identified 1, 8-Cineole, as one of the predominant compound …
Evaluation of in vitro anticancer activity of 1, 8-Cineole–containing n-hexane extract of Callistemon citrinus (Curtis) Skeels plant and its apoptotic potential
S Sampath, V Veeramani, GS Krishnakumar… - Biomedicine & …, 2017 - Elsevier
Plants are the source of a variety of secondary metabolites, which are often used in the
anticancer activity. Discovering new anticancer drug from herbal source is more important in …
anticancer activity. Discovering new anticancer drug from herbal source is more important in …
1, 8-Cineole promotes G0/G1 cell cycle arrest and oxidative stress-induced senescence in HepG2 cells and sensitizes cells to anti-senescence drugs
Abstract Aims 1, 8-Cineole is a plant-derived monoterpene and a major constituent of
Eucalyptus essential oil. Previously, we demonstrated that 1, 8-cineole inhibited …
Eucalyptus essential oil. Previously, we demonstrated that 1, 8-cineole inhibited …
Design, synthesis and biological evaluation of novel β-pinene-based thiazole derivatives as potential anticancer agents via mitochondrial-mediated apoptosis …
Y Wang, C Wu, Q Zhang, Y Shan, W Gu, S Wang - Bioorganic chemistry, 2019 - Elsevier
A series of novel β-pinene-based thiazole derivatives were synthesized and characterized
by HRMS, 1 H NMR, and 13 C NMR analyses as potential antineoplastic agents. Derivatives …
by HRMS, 1 H NMR, and 13 C NMR analyses as potential antineoplastic agents. Derivatives …
Indole‐3‐carbinol induces apoptosis in AGS cancer cells via mitochondrial pathway
AA Singh, SH Jo, AT Kiddane… - Chemical Biology & …, 2023 - Wiley Online Library
Indole‐3‐carbinol is produced from the cruciferous vegetables and broadly investigated for
their various biological effects in in‐vitro and in‐vivo aspects. However, the anticancer …
their various biological effects in in‐vitro and in‐vivo aspects. However, the anticancer …
Apoptotic Cell Death via Activation of DNA Degradation, Caspase-3 Activity, and Suppression of Bcl-2 Activity: An Evidence-Based Citrullus colocynthis Cytotoxicity …
The objectives of this study are to investigate the cytotoxic effect of different Citrullus
colocynthis extracts on breast and lung cancer cell lines using flow cytometry to gain …
colocynthis extracts on breast and lung cancer cell lines using flow cytometry to gain …
Indole-3-carbinol (I3C)-induced apoptosis in nasopharyngeal cancer cells through Fas/FasL and MAPK pathway
Y Xu, J Zhang, WG Dong - Medical Oncology, 2011 - Springer
The apoptotic effects of indole-3-carbinol (I3C) were exhibited in many human cancer cells.
However, the apoptotic effects of I3C on nasopharyngeal cancer cells were still unknown. In …
However, the apoptotic effects of I3C on nasopharyngeal cancer cells were still unknown. In …
Mechanism of piperine in affecting apoptosis and proliferation of gastric cancer cells via ROS‐mitochondria‐associated signalling pathway
L Guo, Y Yang, YJ Sheng, J Wang… - Journal of Cellular …, 2021 - Wiley Online Library
Piperine (PIP), the main active ingredient in pepper, belongs to the cinnamamide alkaloid.
PIP has been found to have functions, including anti‐oxidation, immune regulation, anti …
PIP has been found to have functions, including anti‐oxidation, immune regulation, anti …
Peimine‐induced apoptosis and inhibition of migration by regulating reactive oxygen species‐mediated MAPK/STAT3/NF‐κB and Wnt/β‐catenin signaling pathways …
T Zhang, GY Liu, JL Cao, YN Li, H Xue… - Drug Development …, 2022 - Wiley Online Library
Peimine (PM), a natural product extracted from Fritillaria, has anti‐inflammatory, drug
resistance reversal, and other pharmacological effects. The purpose of this study was to …
resistance reversal, and other pharmacological effects. The purpose of this study was to …
Furanodiene induces G2/M cell cycle arrest and apoptosis through MAPK signaling and mitochondria-caspase pathway in human hepatocellular carcinoma cells
Y Xiao, Y Feng-Qing, L Shao-Ping… - Cancer Biology & …, 2007 - Taylor & Francis
Furanodiene (C15H20O), a pure compound isolated from Traditional Chinese medicine,
Curcuma wenyujin, named Ezhu in Chinese, which structure was determined on the basis of …
Curcuma wenyujin, named Ezhu in Chinese, which structure was determined on the basis of …