Demonstration of Genetic Exchange During Cyclical Development of Leishmania in the Sand Fly Vector
NS Akopyants, N Kimblin, N Secundino, R Patrick… - Science, 2009 - science.org
Genetic exchange has not been shown to be a mechanism underlying the extensive
diversity of Leishmania parasites. We report here evidence that the invertebrate stages of …
diversity of Leishmania parasites. We report here evidence that the invertebrate stages of …
[HTML][HTML] A cell-surface phylome for African trypanosomes
AP Jackson, HC Allison, JD Barry… - PLoS neglected …, 2013 - journals.plos.org
The cell surface of Trypanosoma brucei, like many protistan blood parasites, is crucial for
mediating host-parasite interactions and is instrumental to the initiation, maintenance and …
mediating host-parasite interactions and is instrumental to the initiation, maintenance and …
[HTML][HTML] Paratrypanosoma is a novel early-branching trypanosomatid
The kinetoplastids are a widespread and important group of single-celled eukaryotes, many
of which are devastating parasites of animals, including humans [1–3]. We have discovered …
of which are devastating parasites of animals, including humans [1–3]. We have discovered …
Gene expression in Trypanosoma brucei: lessons from high-throughput RNA sequencing
Trypanosoma brucei undergoes major biochemical and morphological changes during its
development from the bloodstream form in the mammalian host to the procyclic form in the …
development from the bloodstream form in the mammalian host to the procyclic form in the …
Trypanosomes as a magnifying glass for cell and molecular biology
Abstract The African trypanosome, Trypanosoma brucei, has developed into a flexible and
robust experimental model for molecular and cellular parasitology, allowing us to better …
robust experimental model for molecular and cellular parasitology, allowing us to better …
[HTML][HTML] The trypanosome transcriptome is remodelled during differentiation but displays limited responsiveness within life stages
VL Koumandou, SKA Natesan, T Sergeenko, MC Field - BMC genomics, 2008 - Springer
Background Trypanosomatids utilise polycistronic transcription for production of the vast
majority of protein-coding mRNAs, which operates in the absence of gene-specific …
majority of protein-coding mRNAs, which operates in the absence of gene-specific …
[HTML][HTML] Genome-wide subcellular protein map for the flagellate parasite Trypanosoma brucei
K Billington, C Halliday, R Madden, P Dyer… - Nature …, 2023 - nature.com
Trypanosoma brucei is a model trypanosomatid, an important group of human, animal and
plant unicellular parasites. Understanding their complex cell architecture and life cycle is …
plant unicellular parasites. Understanding their complex cell architecture and life cycle is …
[HTML][HTML] Transcriptome Remodeling in Trypanosoma cruzi and Human Cells during Intracellular Infection
Y Li, S Shah-Simpson, K Okrah, AT Belew… - PLoS …, 2016 - journals.plos.org
Intracellular colonization and persistent infection by the kinetoplastid protozoan parasite,
Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global …
Trypanosoma cruzi, underlie the pathogenesis of human Chagas disease. To obtain global …
Phylogeny of trypanosomes as inferred from the small and large subunit rRNAs: implications for the evolution of parasitism in the trypanosomatid protozoa
Sequences of the small rRNA genes and partial sequences of the large rRNA genes were
obtained by PCR amplification from a variety of vertebrate trypanosomes. The trypanosome …
obtained by PCR amplification from a variety of vertebrate trypanosomes. The trypanosome …
Developmental Progression to Infectivity in Trypanosoma brucei Triggered by an RNA-Binding Protein
NG Kolev, K Ramey-Butler, GAM Cross, E Ullu… - Science, 2012 - science.org
Unraveling the intricate interactions between Trypanosoma brucei, the protozoan parasite
causing African trypanosomiasis, and the tsetse (Glossina) vector remains a challenge …
causing African trypanosomiasis, and the tsetse (Glossina) vector remains a challenge …