Autoantibody formation directed against phospholipase A2 receptor (PLA2R) 1 is the
underlying etiology in most cases of primary membranous glomerulopathy. This new …

Background Antibodies against phospholipase A 2 receptor 1 (PLA 2 R1) are found in 80%
of patients with membranous nephropathy, and previous studies described three …

Objectives: Autoantibodies against the M-type phospholipase A2 receptor 1 (anti-PLA2R1)
have been demonstrated to be very specific for idiopathic membranous nephropathy (MN) …

Background Antibodies against M-type phospholipase A2 receptor (PLA2R) are serological
markers of disease activity in patients with idiopathic membranous nephropathy (iMN). To …

Background Idiopathic membranous nephropathy, a common form of the nephrotic
syndrome, is an antibody-mediated autoimmune glomerular disease. Serologic diagnosis …

The M-type phospholipase A2 receptor (PLA 2 R) is the major target antigen in idiopathic
membranous nephropathy with detectable autoantibodies in the serum of up to 70% of …

Membranous nephropathy (MN) accounts for most cases of the nephrotic syndrome in
adults. Recently, studies on the underlying pathomechanisms led to the identification of the …

Kidney biopsy is the gold standard to diagnose membranous nephropathy (MN).
Approximately 70%-80% of patients with primary MN have anti-phospholipase A2 receptor …

Results 77.8% of iMN patients in our cohort had antibodies reactive with human PLA 2 R.
The antibody levels in these patients correlated strongly with both clinical status and …

Background: Anti-phospholipase A2 receptor antibody (PLA2R-Ab) is useful in diagnosing
idiopathic membranous nephropathy (IMN). We investigated the clinical relevance of PLA2R …