Antioxidant pre-treatment reduces the toxic effects of oxalate on renal epithelial cells in a cell culture model of urolithiasis

T Kizivat, M Smolić, I Marić, M Tolušić Levak… - International journal of …, 2017 - mdpi.com
Urolithiasis is characterized by the formation and retention of solid crystals within the urinary
tract. Kidney stones are mostly composed of calcium oxalate, which predominantly …

Antioxidant therapy prevents ethylene glycol-induced renal calcium oxalate crystal deposition in Wistar rats

MR Naghii, E Eskandari, M Mofid, M Jafari… - … urology and nephrology, 2014 - Springer
Purpose Renal epithelial cell injury by reactive oxygen species is a prerequisite step in the
pathogenesis of urolithiasis, and there is increasing evidence that reactive oxygen species …

Identification of myeloperoxidase, α-defensin and calgranulin in calcium oxalate renal stones

S Mushtaq, AA Siddiqui, ZA Naqvi, A Rattani, J Talati… - Clinica chimica acta, 2007 - Elsevier
BACKGROUND: In order to understand the mechanism of stone genesis, it is essential to
determine the characteristics of macromolecules constituting the urinary stones. We …

Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium …

A Albert, V Tiwari, E Paul, D Ganesan… - Journal of Enzyme …, 2017 - Taylor & Francis
Oxalates stimulate alterations in renal epithelial cells and thereby induce calcium oxalate
(CaOx) stone formation. Bacillus subtilis YvrK gene encodes for oxalate decarboxylase …

Micro-elemental analysis and characterization of major heavy metals and trace elements in the urinary stones collected from patients living in diverse geographical …

M Abdel-Gawad, B Ali-El-Dein, E Elsobky… - … Science and Pollution …, 2022 - Springer
In the process of urinary stone formation, several heavy metals and trace elements (HMTE)
have been identified among the major constituents of the calculi. The micro-elements within …

Potential role of glutathione S‑transferase M1 gene polymorphism in kidney calcium oxalate stone formation

K Tang, S Xu, P Chen, J Cai, T Huang, M Liu… - … Urology and Nephrology, 2024 - Springer
Background The purpose of this study was to look into the effects of glutathione S-
transferase M1 (GSTM1) gene polymorphism on the formation of kidney calcium oxalate …

Major and trace elements in human kidney stones: a preliminary investigation in Beijing, China

Y Tian, G Han, R Qu, C Xiao - Minerals, 2022 - mdpi.com
Kidney stone disease affects people globally, with its prevalence on the rise. Given the
importance of elements' function in formation of kidney stones, this study investigated major …

Do teas rich in antioxidants reduce the physicochemical and peroxidative risk factors for calcium oxalate nephrolithiasis in humans? Pilot studies with Rooibos herbal …

A Rodgers, M Mokoena, I Durbach, J Lazarus… - Urolithiasis, 2016 - Springer
Several experimental and animal studies have demonstrated that substances rich in
antioxidants can reduce the physicochemical and peroxidative risk factors for calcium …

Investigation of the link between the type and concentrations of heavy metals and other elements in blood and urinary stones and their association to the …

A Dargahi, S Rahimpouran, HM Rad, E Eghlimi… - Journal of Trace …, 2023 - Elsevier
Background Kidney and urinary tract stones are among the most common and important
health problems, the prevalence of which is increasing nowadays due to a sedentary …

Effects of Klotho protein, vitamin D, and oxidative stress parameters on urinary stone formation and recurrence

E Gürtan, L Işıkay, AY Göçmen, E Güdük, S Sarı… - … Urology and Nephrology, 2024 - Springer
Purpose The present study aimed to investigate the effects of α-Klotho and oxidative stress
markers on urinary stone disease (USD) and demonstrate their use as biochemical markers …