Heart failure (HF) is a major public health problem characterized by inability of the heart to
maintain sufficient output of blood. The systematic characterization of circulating proteins …

Circulating protein biomarkers provide information regarding pathways in heart failure (HF)
and can add important value to clinicians. Advancements in proteomics allow researchers to …

Background: Heart failure (HF) is the most common long-term complication of acute
myocardial infarction (MI). Understanding plasma proteins associated with post-MI HF and …

Background: Circulating biomarkers can facilitate diagnosis and risk stratification for
complex conditions such as heart failure (HF). Newer molecular platforms can accelerate …

We measured serum levels of 4076 unique proteins at baseline in a subset of patients from
the ATMOSPHERE (Efficacy and Safety of Aliskiren and Aliskiren/Enalapril Combination on …

Background: We used a large-scale, high-throughput DNA aptamer-based discovery
proteomic platform to identify circulating biomarkers of cardiac remodeling and incident …

In‐depth proteomic analyses offer a systematic way to investigate protein alterations in
disease and, as such, can be a powerful tool for the identification of novel biomarkers. Here …

Background Chronic kidney disease (CKD) confers increased cardiovascular risk, not fully
explained by traditional factors. Proteins regulate biological processes and inform the risk of …

Heart failure (HF) remains a main cause of mortality worldwide. Risk stratification of patients
with systolic chronic HF is critical to identify those who may benefit from advanced HF …

Background There is a growing recognition of the inherent limitations of the use of the left
ventricular ejection fraction (LVEF) to accurately phenotype patients with heart failure (HF) …