Occurrence of neural tube defects among first‐, second‐, and third‐degree relatives of probands: Results of a United States study

HV Toriello, JV Higgins, JM Opitz - American Journal of Medical …, 1983 - Wiley Online Library
Data on the occurrence of neural tube defects in first‐, second‐, and third‐degree relatives
of probands were collected in a United States study. The proportions of affected individuals …

Etiologic heterogeneity of neural tube defects. II. Clues from family studies.

MJ Khoury, JD Erickson, LM James - American Journal of Human …, 1982 - ncbi.nlm.nih.gov
We previously reported that among neural tube defects (NTDs) with no known causes the
ones that occur alone (singles) have different epidemiologic characteristics from those that …

Recurrence risks for neural tube defects in a genetic counseling clinic population.

MJ Seller - Journal of Medical Genetics, 1981 - jmg.bmj.com
The recurrence of neural tube defects (NTD) in the sib following the index case of all patients
who consulted the South-East Thames Regional Health Authority Genetics Centre in the …

Recurrence risk after neural tube defects in a genetic counselling clinic.

A Czeizel, J Métneki - Journal of medical genetics, 1984 - jmg.bmj.com
The recurrence of isolated neural tube defects in a population of women from a genetic
counselling clinic was found to be 3.4%. After one baby with a neural tube defect the …

The recurrence risk for neural tube defects in the United States: a collaborative study

S Cowchock, E Ainbender, G Prescott… - American journal of …, 1980 - Wiley Online Library
To determine the recurrence risk for patients with one prior pregnancy affected with neural
tube defects (NTD), the authors have pooled date from eight testing centers. In 831 …

Sibs of probands with neural tube defects—a study in the Federal Republic of Germany

M Koch, W Fuhrmann - Human genetics, 1985 - Springer
Data for the risk of neural tube defects in sibs of affected children are needed for genetic
counselling, for decision on prenatal studies, and for planning of preventive measures. Data …

Phenotypic heterogeneity in neural tube defects: a clue to causal heterogeneity

RA Martin, RM Fineman, LB Jorde… - American Journal of …, 1983 - Wiley Online Library
We report here retrospective data on 991 liveborn and stillborn infants with neural tube
defects (NTDs) born to Utah residents from January 1, 1940 to December 31, 1979. Data …

An epidemiologic study of neural tube defects in Los Angeles County II. Etiologic factors in an area with low prevalence at birth

LE Sever - Teratology, 1982 - Wiley Online Library
Epidemiologic characteristics of neural tube defect (NTD) births occurring in Los Angeles
County, California, residents during the period 1966–1972 are presented. The prevalence at …

Studies in neural tube defects I. Epidemiologic and etiologic aspects

NC Myrianthopoulos, M Melnick… - American journal of …, 1987 - Wiley Online Library
Abstract In the NIH Collaborative Perinatal Project, a prospective study of over 53,000
pregnant women and their offspring, 71 single‐born children (13.33/10,000) were found to …

Neural tube defects among twin births.

GC Windham, LE Sever - American Journal of Human Genetics, 1982 - ncbi.nlm.nih.gov
To obtain accurate, unbiased rates of neural tube defects (NTDs) in twins, we conducted a
population-based study that included live births and fetal deaths in Los Angeles County …