Given the array of adverse health consequences of obesity, including increased risk for type
2 diabetes mellitus (T2DM) and cardiovascular disease (CVD), the Look AHEAD trial (N …

Objective The Action for Health in Diabetes (Look AHEAD) trial was a randomized trial
comparing effects of intensive lifestyle intervention (ILI) and diabetes support and education …

Background Weight loss is recommended for overweight or obese patients with type 2
diabetes on the basis of short-term studies, but long-term effects on cardiovascular disease …

OBJECTIVE Look AHEAD (Action for Health in Diabetes) Study is a 16-center randomized
clinical trial in overweight and obese individuals with type 2 diabetes designed to evaluate …

Abstract Look AHEAD (Action for Health in Diabetes) was a randomized controlled trial that
examined the impact of long-term participation in an intensive weight loss intervention on …

OBJECTIVE Look AHEAD, a randomized trial comparing intensive lifestyle intervention (ILI)
and diabetes support and education (DSE)(control) in 5,145 individuals with …

Overweight and obesity are major contributors to both type 2 diabetes and cardiovascular
disease (CVD). Moreover, individuals with type 2 diabetes who are overweight or obese are …

The Look AHEAD trial was a randomized controlled trial comparing an intensive lifestyle
intervention (ILI) to diabetes support and education (DSE) in overweight and obese type 2 …

OBJECTIVE—The effectiveness of intentional weight loss in reducing cardiovascular
disease (CVD) events in type 2 diabetes is unknown. This report describes 1-year changes …

Background Lifestyle interventions produce short-term improvements in glycemia and
cardiovascular disease (CVD) risk factors in individuals with type 2 diabetes mellitus, but no …