Background Specific subcutaneous immunotherapy (SCIT) can achieve long-term remission
in patients with allergic rhinitis (AR) through complex and still unknown mechanisms. The …

Background: Few studies have directly compared the immunologic responses to specific
subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT). Objective: We …

Background Allergen immunotherapy is the only etiological treatment for allergic rhinitis.
Objective To analyze the efficacy, safety, and mechanism of subcutaneous immunotherapy …

Background There is a continuing debate about whether monoallergen subcutaneous
immunotherapy (SCIT) is able to modulate immune and clinical responses toward main …

Background The modulations of lymphocyte subsets and cytokine production due to
subcutaneous allergen immunotherapy (SCIT) are not fully clarified. Objective We …

Background Allergic rhinitis (AR) impairs quality of life and affects nearly 40% of the
Japanese population. Sublingual immunotherapy (SLIT) is the disease‐modifying treatment …

Introduction Our prior clinical study assessed the efficacy and safety of sublingual
immunotherapy (SLIT) with standardized Dermatophagoides farina drops on patients with …

Background We recently reported that human blood dendritic cells from allergic subjects
have impaired IFN‐α production following toll‐like receptor 9 (TLR9)‐dependent innate …

Background Allergen-specific immunotherapy (AIT) is an effective treatment for allergic
rhinitis (AR). During the course of AIT, many biomarkers in body fluids change. It is …

Allergic asthma is a disease characterized by persistent allergen-driven airway
inflammation, remodeling, and airway hyperresponsiveness. CD4+ T-cells, especially T …