[HTML][HTML] Development and optimization of freeze-dried eye drops derived from plasma rich in growth factors technology

E Anitua, M De la Fuente, I Alcalde… - … Vision Science & …, 2020 - iovs.arvojournals.org
Purpose: To investigate whether plasma rich in growth factors (PRGF) eye drops maintain
their biological potential after a freeze drying process. The addition of a lyoprotectant like …

Short-and long-term stability of plasma rich in growth factors eye drops

E Anitua, M de la Fuente, F Muruzábal… - Cornea, 2021 - journals.lww.com
Purpose: To analyze whether plasma rich in growth factors (PRGFs) eye drops preserve
their activity and biological properties after storage for 9 and 12 months at− 20 C, and at 4 C …

Preservation of biological activity of plasma and platelet-derived eye drops after their different time and temperature conditions of storage

E Anitua, M de la Fuente, A Riestra, J Merayo-Lloves… - Cornea, 2015 - journals.lww.com
Purpose: To analyze whether plasma rich in growth factors (PRGF) eye drops preserve their
biological characteristics and activity after storage for 3 and 6 months at− 20 C, at 4 C, and at …

Effects of heat-treatment on plasma rich in growth factors-derived autologous eye drop

E Anitua, F Muruzabal, M De la Fuente… - Experimental eye …, 2014 - Elsevier
We have developed and characterized a new type of plasma rich in growth factors (PRGF)
derived eye-drop therapy for patients suffering from autoimmune diseases. To determine the …

Plasma rich in growth factors (PRGF) eye drops stimulates scarless regeneration compared to autologous serum in the ocular surface stromal fibroblasts

E Anitua, M De la Fuente, F Muruzabal, A Riestra… - Experimental eye …, 2015 - Elsevier
Autologous serum (AS) eye drops was the first blood-derived product used for the treatment
of corneal pathologies but nowadays PRGF arises as a novel interesting alternative to this …

Stability of freeze-dried plasma rich in growth factors eye drops stored for 3 months at different temperature conditions

E Anitua, M de la Fuente, F Muruzábal… - European Journal …, 2021 - journals.sagepub.com
Purpose: The purpose of this study was to analyze the biological content and activity of
freeze-dried plasma rich in growth factors eye drops after their storage at 4° C and at room …

Differential Protein Content between Fresh and Freeze-Dried Plasma Rich in Growth Factors Eye Drops

E Anitua, A Pino, M Azkargorta, F Elortza… - Biomolecules, 2022 - mdpi.com
The purpose of this study was to analyze the proteomic composition of plasma rich in growth
factors eye drops (PRGF) in comparison to lyophilized PRGF eye drops (PRGF lyo). The …

Plasma rich in growth factors for the treatment of ocular surface diseases

E Anitua, F Muruzabal, M de la Fuente… - Current eye …, 2016 - Taylor & Francis
Purpose: The purpose of this work is to describe and review the technology of plasma rich in
growth factors (PRGF), a novel blood derivative product, in the treatment of ocular surface …

Plasma rich in growth factors (PRGF-Endoret) stimulates corneal wound healing and reduces haze formation after PRK surgery

E Anitua, F Muruzabal, I Alcalde… - Experimental eye …, 2013 - Elsevier
This study evaluated the efficacy of Plasma rich in growth factors (PRGF-Endoret) on the
corneal wound healing process after Photorefractive keratectomy (PRK). To address this …

Biological stability of plasma rich in growth factors eye drops after storage of 3 months

E Anitua, F Muruzabal, A Pino, J Merayo-Lloves… - Cornea, 2013 - journals.lww.com
Purpose: We evaluated whether plasma rich in growth factors eye drops maintain their
composition and biological activity after storage for 3 months at− 20 C and after storage at 4 …