[HTML][HTML] YAP knockdown inhibits proliferation and induces apoptosis of human prostate cancer DU145 cells

X Jin, W Zhao, P Zhou, T Niu - Molecular medicine …, 2018 - spandidos-publications.com
The role of yes-associated protein (YAP) in human prostate cancer DU145 cells and its
underlying molecular mechanisms were explored in the present study. Initially, the …

YAP is closely correlated with castration-resistant prostate cancer, and downregulation of YAP reduces proliferation and induces apoptosis of PC-3 cells

X Sheng, WB Li, DL Wang… - Molecular …, 2015 - spandidos-publications.com
Yes-associated protein 65 (YAP65) has been implicated as an oncogene, and its expression
is increased in human cancer. Previous studies have demonstrated that alterations in YAP …

Downregulation of YAP inhibits proliferation, invasion and increases cisplatin sensitivity in human hepatocellular carcinoma cells

X Wang, B Wu, Z Zhong - Oncology Letters, 2018 - spandidos-publications.com
Yes‑associated protein (YAP) serves an essential role in tumorigenesis. However, the
potential role and the molecular mechanism underlying the effect of YAP on hepatocellular …

Downregulation of YAP inhibits proliferation and induces apoptosis in Eca‑109 cells

M Cui, Z Li - Experimental and Therapeutic Medicine, 2018 - spandidos-publications.com
A previous study reported that Yes‑associated protein (YAP) gene was overexpressed in
esophageal squamous cell carcinoma (ESCC); however, the exact role of YAP in ESCC …

[HTML][HTML] Yes-associated protein expression is correlated to the differentiation of prostate adenocarcinoma

MG Noh, SS Kim, EC Hwang… - Journal of pathology …, 2017 - synapse.koreamed.org
Background Yes-associated protein (YAP) in the Hippo signaling pathway is a growth
control pathway that regulates cell proliferation and stem cell functions. Abnormal regulation …

[HTML][HTML] Yes-associated protein enhances proliferation and attenuates sensitivity to cisplatin in human gastric cancer cells

T Lu, L Sun, X Zhu - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Background Yes-associated protein (YAP) is upregulated in many cancer types, and its
overexpression is involved in tumor cell proliferation, metastasis and resistance to …

Expression of Yes-associated protein in non-small cell lung cancer and its relationship with clinical pathological factors

L Su, J Yuan, S Yang, X Wei, S Jiang - Chinese medical journal, 2012 - journals.lww.com
Background Yes-associated protein (YAP) plays an important role in signal transduction and
gene transcription regulation in normal cells, with elevated and over-expressed YAP levels …

Expression and Yes-associated protein in gastric adenocarcinoma and inhibitory effects of its knockdown on gastric cancer cell proliferation and metastasis

J Zhang, ZP Xu, YC Yang, JS Zhu… - International journal …, 2012 - journals.sagepub.com
Yes-associated protein (YAP) has been implicated as an oncogene in multiple human
cancers. In the present study, human gastric adenocarcinoma tissues of different grades (N …

YAP overexpression promotes the epithelial-mesenchymal transition and chemoresistance in pancreatic cancer cells

Y Yuan, D Li, H Li, L Wang… - Molecular medicine …, 2016 - spandidos-publications.com
The expression of Yes-associated protein (YAP) has been reported to be dysregulated in
pancreatic cancer. However, its contributions to tumor formation and progression remain to …

YAP1 is involved in tumorigenic properties of prostate cancer cells

FK Collak, U Demir, F Sagir - Pathology & Oncology Research, 2020 - Springer
Abstract The Yes Associated Protein 1 (YAP1) is a transcriptional cofactor negatively
regulated by Hippo Pathway. The dysregulation of the pathway has been shown to have a …