LncRNA-MALAT1 promotes neovascularization in diabetic retinopathy through regulating miR-125b/VE-cadherin axis

P Liu, SB Jia, JM Shi, WJ Li, LS Tang, XH Zhu… - Bioscience …, 2019 - portlandpress.com
Background: Diabetic retinopathy (DR) is currently the leading cause of blindness and visual
disability in adults with diabetes mellitus (DM). Neovascularization has been identified as an …

MALAT1 modulates TGF-β1-induced endothelial-to-mesenchymal transition through downregulation of miR-145

Y Xiang, Y Zhang, Y Tang, Q Li - Cellular physiology and biochemistry, 2017 - karger.com
Abstract Background/Aims: Endothelial-to-mesenchymal transition (EndMT) plays significant
roles under various pathological conditions including cardiovascular diseases, fibrosis, and …

[HTML][HTML] miRNA-29a inhibits atherosclerotic plaque formation by mediating macrophage autophagy via PI3K/AKT/mTOR pathway

W Shao, S Wang, X Wang, L Yao, X Yuan… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Background: miR-29a plays a vital role in AS, but the relationship between the miR-29a-
targeted PI3K signaling pathway and AS remains unclear. Therefore, this study was carried …

Long non-coding RNA MALAT1 promotes angiogenesis and immunosuppressive properties of HCC cells by sponging miR-140

ZH Hou, XW Xu, XY Fu, LD Zhou… - American Journal of …, 2020 - journals.physiology.org
Hepatocellular carcinoma (HCC) is the most prevalent primary liver cancer in adults.
Previous studies in our laboratory found that long non-coding RNA metastasis-associated …

p53-dependent LincRNA-p21 protects against proliferation and anti-apoptosis of vascular smooth muscle cells in atherosclerosis by upregulating SIRT7 via microRNA …

H Wang, F He, B Liang, Y Jing, P Zhang, W Liu… - Journal of …, 2021 - Springer
This study investigated the functional role of p53-lincRNA-p21 in atherosclerosis (AS) by
mediating the microRNA-17-5p (miR-17-5p)/SIRT7 axis. Peripheral blood was collected …

LncRNA MALAT1 accelerates non‐small cell lung cancer progression via regulating miR‐185‐5p/MDM4 axis

D Wang, S Zhang, M Zhao, F Chen - Cancer medicine, 2020 - Wiley Online Library
Non‐small cell lung cancer (NSCLC) is the commonest malignancy with high death rate
around the world. LncRNA metastasis‐associated lung adenocarcinoma transcript 1 …

LncRNA MALAT1 promotes osteoarthritis by modulating miR-150-5p/AKT3 axis

Y Zhang, F Wang, G Chen, R He, L Yang - Cell & bioscience, 2019 - Springer
Background Many studies have reported that long noncoding RNAs (lncRNAs) could act as
sponges for microRNAs (miRNAs) and play important roles in the regulation of osteoarthritis …

M1 Bone Marrow‐Derived Macrophage‐Derived Extracellular Vesicles Inhibit Angiogenesis and Myocardial Regeneration Following Myocardial Infarction via the …

B Chen, L Luo, X Wei, D Gong, Z Li, S Li… - Oxidative Medicine …, 2021 - Wiley Online Library
Myocardial infarction (MI) is a severe cardiovascular disease. Some M1 macrophage‐
derived extracellular vesicles (EVs) are involved in the inhibition of angiogenesis and …

lncRNA MALAT1 promotes renal fibrosis in diabetic nephropathy by targeting the miR-2355-3p/IL6ST axis

H Huang, G Zhang, Z Ge - Frontiers in pharmacology, 2021 - frontiersin.org
Long noncoding RNA (lncRNAs) metastasis–associated lung adenocarcinoma transcript 1
(MALAT1) has been reported in diabetic nephropathy (DN) about its effect on podocyte …

Long noncoding RNA Malat1 is a potent autophagy inducer protecting brain microvascular endothelial cells against oxygen-glucose deprivation/reoxygenation …

Z Li, J Li, N Tang - Neuroscience, 2017 - Elsevier
Brain microvascular endothelial cell (BMEC) injury induced by ischemia–reperfusion (I/R) is
the initial stage of blood–brain barrier (BBB) disruption, which results in a poor prognosis in …