We used surface plasmon resonance to study the binding of a set of soluble mouse IE class
II major histocompatlblllty molecules, each occupied by a different single peptide, to the …

Nine independent pigeon cytochrome c-specific T cell clones were analyzed by using a
panel of antigenic peptide analogs presented in association with three allelic IE-encoded …

The antigen-specific receptor of T (ymphoc'ytes (TCR) and the Fab moiety of
immunoglobulins are expected to fold into similar threedimensional structures because of …

The enterotoxins produced by Staphylococcus aureus are the most potent mitogens known.
They belong to a group of distantly related mitogenic toxins that differ in other biologic …

The ability of the staphylococcal enterotoxins to stimulate T cells has been thought to
depend on their association with class II MHC products. Here, we demonstrate that a …

Cytotoxic T cells recognize mosaic structures consisting of target peptides embedded within
self-major histocompatibility complex (MHC) class I molecules. This structure has been …

Several bacterial proteins have been recently identified as superantigens which stimulate
large numbers of T cells expressing particular T-cell receptor (TCR) Vβ elements. This …

Antigen recognition by T lymphocytes is mediated by cell-surface glycoproteins known as T-
cell antigen receptors (TCRs). These are composed of α and β, or γ and δ, polypeptide …

The TCR is predicted to resemble the Fab fragment of an Ig molecule and by analogy to
possess six Ag binding loops that contact MHC proteins bound with antigenic peptides. We …

Dendritic cells are potent antigen-presenting cells for several primary immune responses
and therefore provide an opportunity for evaluating the amounts of cell-associated antigens …