Interaction of Aspergillus fumigatus with the alveolar macrophage

M Dubourdeau, R Athman, V Balloy, B Philippe… - Medical …, 2006 - Taylor & Francis
Aspergillus fumigatus is a human pathogen, able to cause invasive aspergillosis in
immunosuppressed patients. In the immunocompetent situation inhaled conidia are easily …

Aspergillus fumigatus induces innate immune responses in alveolar macrophages through the MAPK pathway independently of TLR2 and TLR4

M Dubourdeau, R Athman, V Balloy… - The Journal of …, 2006 - journals.aai.org
Aspergillus fumigatus causes invasive aspergillosis in immunosuppressed patients. In the
immunocompetent host, inhaled conidia are cleared by alveolar macrophages. The …

Role of cytokines against invasive aspergillosis: evidence from preclinical studies

E Roilides, J Meletiadis - Reviews and Research in Medical …, 2003 - journals.lww.com
Aspergillus fumigatus is the most frequent causative agent of invasive aspergillosis, a
predominant life-threatening opportunistic infection in immunocompromised individuals. A …

Interaction of the pathogenic mold Aspergillus fumigatus with lung epithelial cells

N Osherov - Frontiers in microbiology, 2012 - frontiersin.org
Aspergillus fumigatus is an opportunistic environmental mold that can cause severe allergic
responses in atopic individuals and poses a life-threatening risk for severely …

Aspergillus fumigatus germ tube growth and not conidia ingestion induces expression of inflammatory mediator genes in the human lung epithelial cell line A549

AP Bellanger, L Millon, K Khoufache… - Journal of Medical …, 2009 - microbiologyresearch.org
Inhalation of conidia is the main cause of invasive pulmonary aspergillosis (IPA) and the
respiratory epithelium is the first line of defence. To explore the triggering factor for the …

Aspergillus fumigatus-induced interleukin-8 synthesis by respiratory epithelial cells is controlled by the phosphatidylinositol 3-kinase, p38 MAPK, and ERK1/2 …

V Balloy, JM Sallenave, Y Wu, L Touqui… - Journal of biological …, 2008 - ASBMB
Previous studies have established that phagocytes are key cells of the pulmonary innate
immune defense against A. fumigatus, an opportunistic fungus responsible of invasive …

[HTML][HTML] The Immune Interplay between the Host and the Pathogen in Aspergillus fumigatus Lung Infection

H Sales-Campos, L Tonani, CRB Cardoso… - BioMed research …, 2013 - hindawi.com
The interplay between Aspergillus fumigatus and the host immune response in lung
infection has been subject of studies over the last years due to its importance in …

[HTML][HTML] Bronchial epithelial cells on the front line to fight lung infection-causing Aspergillus fumigatus

J Bigot, L Guillot, J Guitard, M Ruffin, H Corvol… - Frontiers in …, 2020 - frontiersin.org
Aspergillus fumigatus is an environmental filamentous fungus that can be pathogenic for
humans, wherein it is responsible for a large variety of clinical forms ranging from allergic …

Cytokine and chemokine responses following pulmonary challenge with Aspergillus fumigatus: obligatory role of TNF-alpha and GM-CSF in neutrophil recruitment.

S Schelenz, DA Smith, GJ Bancroft - Medical mycology, 1999 - europepmc.org
Aspergillus fumigatus causes life-threatening invasive pulmonary aspergillosis in the
immunocompromised patient. In this study we have used a murine model of intratracheal …

Acute Lung Injury and Repair Induced by Single Exposure of Aspergillus Fumigatus in Immunocompetent Mice

NLSO Malacco, JAM Souza, AC Mendes… - Future …, 2019 - Taylor & Francis
Aim: Characterize the course of acute Aspergillus fumigatus lung infection in
immunocompetent mice, investigating the immunological, pathological and tissue functional …