Invasive aspergillosis (IA) is one of the most difficult to treat and, consequently, one of the
most lethal fungal infections known to man. Continued use of immunosuppressive agents …

The opportunistic human pathogenic fungus Aspergillus fumigatus (Af) causes the majority
of cases of invasive aspergillosis. Because Af enters the human body through inhalation of …

Aim: Aspergillus fumigatus is one of the most common opportunistic fungi that can cause
invasive infection. To profile the kinetic variation of immune cells and cytokines after …

Cytokines are critical molecules necessary for normal lung pathogen host defences. Gamma
interferon (IFN-γ) and T1-phenotype immune responses are important components of host …

OBJECTIVE: To study the interaction of airway epithelial cell line A549 with fragments of
mycelium, spores of Aspergillus fumigatus in vitro and to determine if toll-like receptors …

Invasive pulmonary aspergillosis induced by the pathogenic fungus Aspergillus fumigatus is
one of the common fatal complications in immunocompromised patients. Lung epithelial …

Aspergillus fumigatus is known as a cause of multiple airway diseases that range from
harmless saprophytic colonization (presence of the fungus in sputum of healthy individuals) …

Aspergillus moulds exist ubiquitously as spores that are inhaled in large numbers daily.
Whilst most are removed by anatomical barriers, disease may occur in certain …

Fungal infections, including those by Aspergillus fumigatus, have become more prevalent in
recent years. Intensified medical treatment causing iatrogenic immunosuppression (eg in …

Despite the development of new treatments, the mortality due to invasive pulmonary
aspergillosis remains above 50%, reaching 95% in certain situations. The battle against …