Evolution of the immune response to chronic airway colonization with Aspergillus fumigatus hyphae

M Urb, BD Snarr, G Wojewodka, M Lehoux… - Infection and …, 2015 - Am Soc Microbiol
Airway colonization by the mold Aspergillus fumigatus is common in patients with underlying
lung disease and is associated with chronic airway inflammation. Studies probing the …

Validation of a simplified in vitro Transwell® model of the alveolar surface to assess host immunity induced by different morphotypes of Aspergillus fumigatus

CO Morton, S Wurster, M Fliesser, F Ebel… - International Journal of …, 2018 - Elsevier
Interactions between fungal pathogens such as Aspergillus fumigatus with host alveolar
epithelium and innate immune cells are crucial in the defense against opportunistic fungal …

Dexamethasone and cyclosporin A modulation of cytokine expression and specific antibody synthesis in an allergic bronchopulmonary aspergillosis murine model

JM Wang, HW Chu, M Bosse… - European journal of …, 1996 - Wiley Online Library
We previously demonstrated that, in C57B1/6 mice, cyclosporin A enhanced and
dexamethasone inhibited the Aspergillus fumigatus‐induced pulmonary eosinophilia and …

Interference of Aspergillus fumigatus with the immune response

T Heinekamp, H Schmidt, K Lapp, V Pähtz… - Seminars in …, 2015 - Springer
Aspergillus fumigatus is a saprotrophic filamentous fungus and also the most prevalent
airborne fungal pathogen of humans. Depending on the host's immune status, the variety of …

Hypoxia attenuates anti‐Aspergillus fumigatus immune responses initiated by human dendritic cells

M Fliesser, M Wallstein, O Kurzai, H Einsele… - Mycoses, 2016 - Wiley Online Library
Aspergillus fumigatus is an opportunistic mould that causes invasive pulmonary
aspergillosis (IPA), a life‐threatening infection in immunocompromised patients. During the …

Aspergillus fumigatus-induced early inflammatory response in pulmonary microvascular endothelial cells: Role of p38 MAPK and inhibition by silibinin

J Song, W Pan, Y Sun, J Han, W Shi, W Liao - International …, 2017 - Elsevier
Human invasive pulmonary aspergillosis (IPA) is a serious infectious disease mainly caused
by Aspergillus fumigatus (A. fumigatus). Pulmonary microvascular endothelial cells …

Cytokine Networking in Lungs of Immunocompetent Mice in Response to Inhaled Aspergillus fumigatus

JK Brieland, C Jackson, F Menzel… - Infection and …, 2001 - Am Soc Microbiol
Cytokine networking in the lung in response to inhaled Aspergillus fumigatus was assessed
using a murine model of primary pulmonary aspergillosis in immunocompetent Crl: CF-1 …

[HTML][HTML] Advances in Aspergillus fumigatus pathobiology

F Lamoth, PR Juvvadi, WJ Steinbach - Frontiers in microbiology, 2016 - frontiersin.org
Aspergillus fumigatus and other Aspergillus spp. are ubiquitous in our environment.
However, their potential to cause severe disease in humans was ignored for many centuries …

Impact of Aspergillus fumigatus in allergic airway diseases

N Chaudhary, KA Marr - Clinical and translational allergy, 2011 - Springer
For decades, fungi have been recognized as associated with asthma and other reactive
airway diseases. In contrast to type I-mediated allergies caused by pollen, fungi cause a …

Exposure to Aspergillus fumigatus spores induces chemokine expression in mouse macrophages

L Pylkkänen, H Gullstén, ML Majuri, U Andersson… - Toxicology, 2004 - Elsevier
Inhalation of fungal spores may cause inflammation and respiratory diseases, such as
bronchitis, allergic alveolitis, and asthma. Alveolar macrophages provide the first line of …